Human COL11A1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	COL11A1
Locus ID	1301
Kit Components	GA100915G1, COL11A1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100915G2, COL11A1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100915G3, COL11A1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001168249, NM_001190709, NM_001854, NM_080629, NM_080630, NR_134980
Synonyms	CO11A1; COLL6; STL2
Summary	This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009]

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