Human Collagen IV (COL4A5) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	COL4A5
Locus ID	1287
Kit Components	GA100901G1, Collagen IV gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100901G2, Collagen IV gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100901G3, Collagen IV gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000495, NM_033380, NM_033381
Synonyms	ASLN; ATS; CA54
Summary	This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]

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