Human Cannabinoid Receptor I (CNR1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CNR1
Locus ID	1268
Kit Components	GA100888G1, Cannabinoid Receptor I gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100888G2, Cannabinoid Receptor I gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100888G3, Cannabinoid Receptor I gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001160226, NM_001160258, NM_001160259, NM_001160260, NM_001840, NM_016083, NM_033181, NM_001365872, NM_001370545, NM_001365869, NM_001365870, NM_001365874, NM_001370546, NM_001370547
Synonyms	CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR
Summary	This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009]

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