Human CLK1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CLK1
Locus ID	1195
Kit Components	GA100854G1, CLK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100854G2, CLK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100854G3, CLK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001024646, NM_001162407, NM_004071, NR_027855, NR_027856
Synonyms	CDC-like kinase 1; CDC28/CDC2-like kinase; CLK; CLK, STY, CLK/STY; CLK/STY; dual specificity protein kinase CLK1; protein tyrosine kinase STY; STY
Summary	This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

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