Human IKK alpha (CHUK) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CHUK
Locus ID	1147
Kit Components	GA100824G1, IKK alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100824G2, IKK alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100824G3, IKK alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001278, NM_001320928
Synonyms	IKBKA; IKK-alpha; IKK1; IKKA; NFKBIKA; TCF16
Summary	This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]

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