Human CHRNB1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CHRNB1
Locus ID	1140
Kit Components	GA100817G1, CHRNB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100817G2, CHRNB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100817G3, CHRNB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000747
Synonyms	ACHRB; CHRNB; CMS1D; CMS2A; CMS2C; SCCMS
Summary	The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008]

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