Human Muscarinic Acetylcholine Receptor M4 (CHRM4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CHRM4
Locus ID	1132
Kit Components	GA100809G1, Muscarinic Acetylcholine Receptor M4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100809G2, Muscarinic Acetylcholine Receptor M4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100809G3, Muscarinic Acetylcholine Receptor M4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000741, NM_001366692
Synonyms	HM4; M4R
Summary	The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]

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