Human CEACAM5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CEACAM5
Locus ID	1048
Kit Components	GA100756G1, CEACAM5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100756G2, CEACAM5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100756G3, CEACAM5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001291484, NM_001308398, NM_004363
Synonyms	CD66e; CEA
Summary	This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

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