Human CCBL1 (KYAT1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KYAT1
Locus ID	883
Kit Components	GA100619G1, CCBL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100619G2, CCBL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100619G3, CCBL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001122671, NM_001122672, NM_001287390, NM_004059, NR_109829, NM_001352988, NM_001352989, NM_001352990, NM_001352991, NM_001352992, NM_001352993, NM_001352994, NM_001352995, NM_001352996, NM_001352997, NM_001352998, NM_001352999, NR_148224, NR_148225
Synonyms	CCBL1; GTK; KAT1; KATI
Summary	This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

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