Human Actin Regulatory Protein CAPG (CAPG) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CAPG
Locus ID	822
Kit Components	GA100575G1, Actin Regulatory Protein CAPG gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100575G2, Actin Regulatory Protein CAPG gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100575G3, Actin Regulatory Protein CAPG gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001256139, NM_001256140, NM_001320732, NM_001320733, NM_001320734, NM_001747
Synonyms	AFCP; HEL-S-66; MCP
Summary	This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012]

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