Human CAMK2B activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CAMK2B
Locus ID	816
Kit Components	GA100569G1, CAMK2B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100569G2, CAMK2B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100569G3, CAMK2B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001220, NM_001293170, NM_172078, NM_172079, NM_172080, NM_172081, NM_172082, NM_172083, NM_172084
Synonyms	CAM2; CAMK2; CAMKB
Summary	The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

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