Human CALM1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CALM1
Locus ID	801
Kit Components	GA100561G1, CALM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100561G2, CALM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100561G3, CALM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001166106, NM_006888, NM_001363669, NM_001363670
Synonyms	CALM2; CALM3; CALML2; CAMI; DD132; PHKD
Summary	This gene encodes one of three calmodulin proteins which are members of the EF-hand calcium-binding protein family. Calcium-induced activation of calmodulin regulates and modulates the function of cardiac ion channels. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.A missense mutation in the CALM1 gene has been associated with ventricular tachycardia.[provided by RefSeq, May 2020]

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