Human Calcitonin receptor (CALCR) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CALCR
Locus ID	799
Kit Components	GA100559G1, Calcitonin receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100559G2, Calcitonin receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100559G3, Calcitonin receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001164737, NM_001164738, NM_001742
Synonyms	CRT; CT-R; CTR; CTR1
Summary	This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

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