Human CACNA1B activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CACNA1B
Locus ID	774
Kit Components	GA100539G1, CACNA1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100539G2, CACNA1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100539G3, CACNA1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000718, NM_001243812
Synonyms	BIII; CACNL1A5; CACNN; Cav2.2
Summary	The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

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