Human Calpain 5 (CAPN5) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CAPN5
Locus ID	726
Kit Components	GA100504G1, Calpain 5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100504G2, Calpain 5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100504G3, Calpain 5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004055
Synonyms	ADNIV; HTRA3; nCL-3; VRNI
Summary	Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3. [provided by RefSeq, Jul 2008]

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