Human BubR1 (BUB1B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BUB1B
Locus ID	701
Kit Components	GA100487G1, BubR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100487G2, BubR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100487G3, BubR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001211
Synonyms	Bub1A; BUB1beta; BUBR1; hBUBR1; MAD3L; MVA1; SSK1
Summary	This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]

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