Human BCL2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BCL2
Locus ID	596
Kit Components	GA100410G1, BCL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100410G2, BCL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100410G3, BCL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000633, NM_000657
Synonyms	Bcl-2; PPP1R50
Summary	This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

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