Human BACH1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BACH1
Locus ID	571
Kit Components	GA100390G1, BACH1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100390G2, BACH1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100390G3, BACH1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001011545, NM_001186, NM_206866, NR_027655
Synonyms	BACH-1; BTB and CNC homology 1; BTB and CNC homology 1, basic leucine zipper transcription factor 1; OTTHUMP00000096564
Summary	This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009]

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