Human ATP6V0B activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ATP6V0B
Locus ID	533
Kit Components	GA100369G1, ATP6V0B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100369G2, ATP6V0B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100369G3, ATP6V0B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001039457, NM_001294333, NM_004047
Synonyms	ATP6F; HATPL; VMA16
Summary	This gene encodes a portion of the V0 domain of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Activity of this enzyme is necessary for such varied processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

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