Human ARHGAP4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGAP4
Locus ID	393
Kit Components	GA100283G1, ARHGAP4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100283G2, ARHGAP4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100283G3, ARHGAP4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001164741, NM_001666
Synonyms	C1; p115; RGC1; RhoGAP4; SrGAP4
Summary	This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins belonging to the RAS superfamily. The protein encoded by the orthologous gene in rat is localized to the Golgi complex and can redistribute to microtubules. The rat protein stimulates the activity of some Rho GTPases in vitro. Genomic deletions of this gene and a neighboring gene have been found in patients with nephrogenic diabetes insipidus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

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