Human AKT2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	AKT2
Locus ID	208
Kit Components	GA100144G1, AKT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100144G2, AKT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100144G3, AKT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001243027, NM_001243028, NM_001330511, NM_001626
Synonyms	HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA
Summary	This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The gene serves as an oncogene in the tumorigenesis of cancer cells For example, its overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins, and has also been implicated in insulin signaling. [provided by RefSeq, Nov 2019]

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