Human AGRP activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	AGRP
Locus ID	181
Kit Components	GA100127G1, AGRP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100127G2, AGRP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100127G3, AGRP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001138, NM_007316
Synonyms	AGRT; ART; ASIP2
Summary	This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009]

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