Human alpha 1a Adrenergic Receptor (ADRA1A) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ADRA1A
Locus ID	148
Kit Components	GA100102G1, alpha 1a Adrenergic Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100102G2, alpha 1a Adrenergic Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100102G3, alpha 1a Adrenergic Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000680, NM_001322502, NM_001322503, NM_001322504, NM_033302, NM_033303, NM_033304, NR_136343
Synonyms	ADRA1C; ADRA1L1; ALPHA1AAR
Summary	Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]

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