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VEGF Receptor 1 (FLT1) (NM_002019) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC224406L1V
- LentiORF®
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Lenti ORF particles, FLT1 (Myc-DDK tagged) - Human fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (FLT1), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 21,660.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Product Name | VEGF Receptor 1 (FLT1) (NM_002019) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | FLT; FLT-1; VEGFR-1; VEGFR1 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_002019 |
| ORF Size | 4014 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC224406).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_002019.2, NP_002010.2 |
| RefSeq Size | 5777 bp |
| RefSeq ORF | 4017 bp |
| Locus ID | 2321 |
| Domains | pkinase, TyrKc, S_TKc, ig, IGv, IGc2, IG |
| Protein Families | Druggable Genome, Protein Kinase, Secreted Protein |
| Protein Pathways | Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion |
| MW | 150.77 kDa |
| Gene Summary | This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Injured Axons Instruct Schwann Cells to Build Constricting Actin Spheres to Accelerate Axonal Disintegration.
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Cell reports
,PubMed ID 31189102
[FLT1]
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