VE Cadherin (CDH5) (NM_001795) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC223907L1V
- LentiORF®
Lenti ORF particles, CDH5 (Myc-DDK-tagged)-Human cadherin 5, type 2 (vascular endothelium) (CDH5), 200ul, >10^7 TU/mL
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CNY 14,535.00
Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Product Name | VE Cadherin (CDH5) (NM_001795) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | 7B4; CD144 |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_001795 |
ORF Size | 2352 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC223907).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001795.3 |
RefSeq Size | 4134 bp |
RefSeq ORF | 2355 bp |
Locus ID | 1003 |
Domains | Cadherin_C_term, CA |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration |
MW | 87.5 kDa |
Gene Summary | This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq, Nov 2015] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
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Combined implantation of CD34 + and CD14 + cells increases neovascularization through amplified paracrine signalling
,null,
Journal of Tissue Engineering and Regenerative Medicine
,PubMed ID 22125235
[CDH5]
|
Kr?ppel-Like Factor-4 Transcriptionally Regulates VE-cadherin Expression and Endothelial Barrier Function
,null,
Circulation research
,PubMed ID 20724706
[CDH5]
|
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