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RAPGEF2 (NM_014247) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC222055L4V
- LentiORF®
-
Lenti ORF particles, RAPGEF2 (mGFP-tagged)-Human Rap guanine nucleotide exchange factor (GEF) 2 (RAPGEF2), 200ul, >10^7 TU/mL
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CNY 24,035.00
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规格
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Specifications
| Product Data | |
| Product Name | RAPGEF2 (NM_014247) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CNrasGEF; NRAPGEP; nRap GEP; PDZ-GEF1; PDZGEF1; RA-GEF; RA-GEF-1; RAGEF; Rap-GEP |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_014247 |
| ORF Size | 4497 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC222055).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_014247.1, NP_055062.1 |
| RefSeq Size | 6568 bp |
| RefSeq ORF | 4500 bp |
| Locus ID | 9693 |
| Domains | RA, cNMP, RasGEFN, PDZ, RasGEF |
| Protein Pathways | MAPK signaling pathway |
| MW | 167.2 kDa |
| Gene Summary | Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008] |
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