PTPRN (NM_002846) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC220230L4V
- LentiORF®
Lenti ORF particles, PTPRN (mGFP-tagged) - Human protein tyrosine phosphatase, receptor type, N (PTPRN), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 19,095.00
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Specifications
Product Data | |
Product Name | PTPRN (NM_002846) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | IA-2; IA-2/PTP; IA2; ICA512; R-PTP-N |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_002846 |
ORF Size | 2937 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC220230).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_002846.2 |
RefSeq Size | 3649 bp |
RefSeq ORF | 2940 bp |
Locus ID | 5798 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Type I diabetes mellitus |
MW | 105.85 kDa |
Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010] |
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