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ERVWE1 (ERVW-1) (NM_014590) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC213951L1V
- LentiORF®
-
Lenti ORF particles, ERVW (Myc-DDK tagged) - Human endogenous retrovirus group W, member 1 (ERVW-1), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,930.00
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规格
| Cited in 1 publication. |
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Specifications
| Product Data | |
| Product Name | ERVWE1 (ERVW-1) (NM_014590) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | ENV; ENVW; ERVWE1; HERV-7q; HERV-W-ENV; HERV7Q; HERVW; HERVWENV |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_014590 |
| ORF Size | 1614 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC213951).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_014590.3, NP_055405.3 |
| RefSeq Size | 3044 bp |
| RefSeq ORF | 1617 bp |
| Locus ID | 30816 |
| Domains | ENV_polyprotein |
| Protein Families | Transmembrane |
| MW | 59.87 kDa |
| Gene Summary | Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Human Retrotransposons and the Global Shutdown of Homeostatic Innate Immunity by Oncolytic Parvovirus H-1PV in Pancreatic Cancer
,null,
Viruses
,PubMed ID 34071585
[ERVW-1]
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