Caspase 9 (CASP9) (NM_032996) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC213375L3V

  • LentiORF®

Lenti ORF particles, CASP9 (Myc-DDK tagged) - Human caspase 9, apoptosis-related cysteine peptidase (CASP9), transcript variant beta, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 8,170.00


货期*
详询

规格
    • 200 ul

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Specifications

Product Data
Product Name Caspase 9 (CASP9) (NM_032996) Human Tagged ORF Clone Lentiviral Particle
Synonyms APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_032996
ORF Size 798 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC213375).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_032996.1, NP_127463.1
RefSeq Size 1584 bp
RefSeq ORF 1002 bp
Locus ID 842
Protein Families Druggable Genome, Protease, Stem cell - Pluripotency
Protein Pathways Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Endometrial cancer, Huntington's disease, Non-small cell lung cancer, p53 signaling pathway, Pancreatic cancer, Parkinson's disease, Pathways in cancer, Prostate cancer, Small cell lung cancer, VEGF signaling pathway, Viral myocarditis
MW 30 kDa
Gene Summary This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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