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CD160 (NM_007053) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC204886L1V
- LentiORF®
-
Lenti ORF particles, CD160 (Myc-DDK tagged) - Human CD160 molecule (CD160), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | CD160 (NM_007053) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | BY55; NK1; NK28 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_007053 |
| ORF Size | 543 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC204886).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_007053.2 |
| RefSeq Size | 1633 bp |
| RefSeq ORF | 546 bp |
| Locus ID | 11126 |
| Protein Families | Druggable Genome |
| MW | 19.8 kDa |
| Gene Summary | CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008] |
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