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Adcy8 (NM_009623) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR215716L4V
- LentiORF®
-
Lenti ORF particles, Adcy8 (GFP-tagged) - Mouse adenylate cyclase 8 (Adcy8), 200ul, >10^7 TU/mL
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CNY 20,045.00
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Specifications
| Product Data | |
| Product Name | Adcy8 (NM_009623) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AC8; AW060868 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_009623 |
| ORF Size | 3747 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR215716).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_009623.2, NP_033753.2 |
| RefSeq Size | 5064 bp |
| RefSeq ORF | 3750 bp |
| Locus ID | 11514 |
| Gene Summary | Catalyzes the formation of cAMP in response to calcium entry leadings to cAMP signaling activation that affect processes suche as synaptic plasticity and insulin secretion (PubMed:10864938, PubMed:25403481, PubMed:10482244, PubMed:14585998, PubMed:18448650). Plays a role in many brain functions, such as learning, memory, drug addiction, and anxiety modulation through regulation of synaptic plasticity by modulating long-term memory and long-term potentiation (LTP) through CREB transcription factor activity modulation (PubMed:10482244, PubMed:14585998, PubMed:18448650, PubMed:10864938, PubMed:12441059, PubMed:20638449, PubMed:27234425, PubMed:18222416). Plays a central role in insulin secretion by controlling glucose homeostasis through glucagon-like peptide 1 and glucose signaling pathway and maintains insulin secretion through calcium-dependent PKA activation leading to vesicle pool replenishment (PubMed:25403481). Also, allows PTGER3 to induce potentiation of PTGER4-mediated PLA2 secretion by switching from a negative to a positive regulation, during the IL1B induced-dedifferentiation of smooth muscle cells (By similarity).[UniProtKB/Swiss-Prot Function] |
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