Ncapd2 (BC029133) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR211971L3V
- LentiORF®
-
Lenti ORF particles, Ncapd2 (Myc-DDK-tagged) - Mouse non-SMC condensin I complex, subunit D2 (cDNA clone MGC:37090 IMAGE:4951596), 200ul, >10^7 TU/mL
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CNY 20900.00
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Specifications
| Product Data | |
| Product Name | Ncapd2 (BC029133) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | MGC39046, CNAP1, mKIAA0159, CAP-D2 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | BC029133 |
| ORF Size | 4212 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR211971).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC029133.1 |
| RefSeq Size | 4376 bp |
| RefSeq ORF | 4214 bp |
| Locus ID | 68298 |
| Gene Summary | Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of non-centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size.[UniProtKB/Swiss-Prot Function] |
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