Sfrs15 (BC053096) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR211770L3V
- LentiORF®
-
Lenti ORF particles, Sfrs15 (Myc-DDK-tagged) - Mouse splicing factor, arginine/serine-rich 15 (cDNA clone MGC:62487 IMAGE:6401143), 200ul, >10^7 TU/mL
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CNY 15200.00
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Specifications
| Product Data | |
| Product Name | Sfrs15 (BC053096) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AA517739; Sfrs15; Sra4; Srsf15 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | BC053096 |
| ORF Size | 3549 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR211770).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC053096.1 |
| RefSeq Size | 4202 bp |
| RefSeq ORF | 3551 bp |
| Locus ID | 224432 |
| Gene Summary | Anti-terminator protein required to prevent early mRNA termination during transcription. Together with SCAF8, acts by suppressing the use of early, alternative poly(A) sites, thereby preventing the accumulation of non-functional truncated proteins. Mechanistically, associates with the phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit (POLR2A), and subsequently binds nascent RNA upstream of early polyadenylation sites to prevent premature mRNA transcript cleavage and polyadenylation. Independently of SCAF8, also acts as a suppressor of transcriptional readthrough.[UniProtKB/Swiss-Prot Function] |
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