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Edem2 (NM_145537) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR209050L4V
- LentiORF®
-
Lenti ORF particles, Edem2 (GFP-tagged) - Mouse ER degradation enhancer, mannosidase alpha-like 2 (Edem2), 200ul, >10^7 TU/mL
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CNY 11,590.00
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Specifications
| Product Data | |
| Product Name | Edem2 (NM_145537) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 9530090G24Rik; AI327354 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_145537 |
| ORF Size | 1734 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR209050).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_145537.1, NP_663512.1 |
| RefSeq Size | 2294 bp |
| RefSeq ORF | 1734 bp |
| Locus ID | 108687 |
| Gene Summary | Involved in the endoplasmic reticulum-associated degradation (ERAD) pathway that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner (PubMed:15579471, PubMed:25655076). May initiate ERAD by promoting the first mannose trimming step of ERAD substrates, from Man9GlcNAc2 to Man8GlcNAc2 (By similarity). Seems to recognize and bind to exposed hydrophobic regions in target proteins (PubMed:25655076).[UniProtKB/Swiss-Prot Function] |
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