Qk (BC053426) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR205119L3V
- LentiORF®
-
Lenti ORF particles, Qk (Myc-DDK-tagged) - Mouse quaking (cDNA clone MGC:59277 IMAGE:6335004), 200ul, >10^7 TU/mL
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CNY 9975.00
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Specifications
Product Data | |
Product Name | Qk (BC053426) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | QkI, 1500005P18 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | BC053426 |
ORF Size | 1023 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR205119).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | BC053426.1 |
RefSeq Size | 2208 bp |
RefSeq ORF | 1025 bp |
Locus ID | 19317 |
Gene Summary | RNA-binding protein that plays a central role in myelinization (PubMed:10864952, PubMed:11917126). Also required for visceral endoderm function and blood vessel development (PubMed:11892011, PubMed:16470614). Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence (PubMed:16041388). Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, as well as cellular processes including apoptosis, cell cycle, glial cell fate and development (PubMed:10535969, PubMed:12467586, PubMed:11297509, PubMed:11917126, PubMed:15568022). Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation (PubMed:10535969, PubMed:15568022). Participates in mRNA transport by regulating the nuclear export of MBP mRNA (PubMed:12467586). May also play a role in smooth muscle development (PubMed:14706070).[UniProtKB/Swiss-Prot Function] |
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