Prkab1 (NM_031869) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR203594L3V
- LentiORF®
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Lenti ORF particles, Prkab1 (Myc-DDK-tagged) - Mouse protein kinase, AMP-activated, beta 1 non-catalytic subunit (Prkab1), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | Prkab1 (NM_031869) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 1300015D22Rik; AU021155; E430008F22 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_031869 |
ORF Size | 813 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR203594).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_031869.2, NP_114075.1 |
RefSeq Size | 2051 bp |
RefSeq ORF | 813 bp |
Locus ID | 19079 |
Gene Summary | Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3) (By similarity).[UniProtKB/Swiss-Prot Function] |
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