RTEL1 (NM_001283009) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	C20orf41; DKCA4; DKCB5; NHL; PFBMFT3; RTEL
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_001283009, the custom clone sequence may differ by one or more nucleotides ATGCCCAAGATAGTCCTGAATGGTGTGACCGTAGACTTCCCTTTCCAGCCCTACAAATGCCAACAGGAGT ACATGACCAAGGTCCTGGAATGTCTGCAGCAGAAGGTGAATGGCATCCTGGAGAGCCCTACGGGTACAGG GAAGACGCTGTGCCTGCTGTGCACCACGCTGGCCTGGCGAGAACACCTCCGAGACGGCATCTCTGCCCGC AAGATTGCCGAGAGGGCGCAAGGAGAGCTTTTCCCGGATCGGGCCTTGTCATCCTGGGGCAACGCTGCTG CTGCTGCTGGAGACCCCATAGCTTGCTACACGGACATCCCAAAGATTATTTACGCCTCCAGGACCCACTC GCAACTCACACAGGTCATCAACGAGCTTCGGAACACCTCCTACCGGCCTAAGGTGTGTGTGCTGGGCTCC CGGGAGCAGCTGTGCATCCATCCTGAGGTGAAGAAACAAGAGAGTAACCATCTACAGATCCACTTGTGCC GTAAGAAGGTGGCAAGTCGCTCCTGTCATTTCTACAACAACGTAGAAGAAAAAAGCCTGGAGCAGGAGCT GGCCAGCCCCATCCTGGACATTGAGGACTTGGTCAAGAGCGGAAGCAAGCACAGGGTGTGCCCTTACTAC CTGTCCCGGAACCTGAAGCAGCAAGCCGACATCATATTCATGCCGTACAATTACTTGTTGGATGCCAAGA GCCGCAGAGCACACAACATTGACCTGAAGGGGACAGTCGTGATCTTTGACGAAGCTCACAACGTGGAGAA GATGTGTGAAGAATCGGCATCCTTTGACCTGACTCCCCATGACCTGGCTTCAGGACTGGACGTCATAGAC CAGGTGCTGGAGGAGCAGACCAAGGCAGCGCAGCAGGGTGAGCCCCACCCGGAGTTCAGCGCGGACTCCC CCAGCCCAGGGCTGAACATGGAGCTGGAAGACATTGCAAAGCTGAAGATGATCCTGCTGCGCCTGGAGGG GGCCATCGATGCTGTTGAGCTGCCTGGAGACGACAGCGGTGTCACCAAGCCAGGGAGCTACATCTTTGAG CTGTTTGCTGAAGCCCAGATCACGTTTCAGACCAAGGGCTGCATCCTGGACTCGCTGGACCAGATCATCC AGCACCTGGCAGGACGTGCTGGAGTGTTCACCAACACGGCCGGACTGCAGAAGCTGGCGGACATTATCCA GATTGTGTTCAGTGTGGACCCCTCCGAGGGCAGCCCTGGTTCCCCAGCAGGGCTGGGGGCCTTACAGTCC TATAAGGTGCACATCCATCCTGATGCTGGTCACCGGAGGACGGCTCAGCGGTCTGATGCCTGGAGCACCA CTGCAGCCAGAAAGCGAGGGAAGGTGCTGAGCTACTGGTGCTTCAGTCCCGGCCACAGCATGCACGAGCT GGTCCGCCAGGGCGTCCGCTCCCTCATCCTTACCAGCGGCACGCTGGCCCCGGTGTCCTCCTTTGCTCTG GAGATGCAGATCCCTTTCCCAGTCTGCCTGGAGAACCCACACATCATCGACAAGCACCAGATCTGGGTGG GGGTCGTCCCCAGAGGCCCCGATGGAGCCCAGTTGAGCTCCGCGTTTGACAGACGGTTTTCCGAGGAGTG CTTATCCTCCCTGGGGAAGGCTCTGGGCAACATCGCCCGCGTGGTGCCCTATGGGCTCCTGATCTTCTTC CCTTCCTATCCTGTCATGGAGAAGAGCCTGGAGTTCTGGCGGGCCCGCGACTTGGCCAGGAAGATGGAGG CGCTGAAGCCGCTGTTTGTGGAGCCCAGGAGCAAAGGCAGCTTCTCCGAGACCATCAGTGCTTACTATGC AAGGGTTGCCGCCCCTGGGTCCACCGGCGCCACCTTCCTGGCGGTCTGCCGGGGCAAGGCCAGCGAGGGG CTGGACTTCTCAGACACGAATGGCCGTGGTGTGATTGTCACGGGCCTCCCGTACCCCCCACGCATGGACC CCCGGGTTGTCCTCAAGATGCAGTTCCTGGATGAGATGAAGGGCCAGGGTGGGGCTGGGGGCCAGTTCCT CTCTGGGCAGGAGTGGTACCGGCAGCAGGCGTCCAGGGCTGTGAACCAGGCCATCGGGCGAGTGATCCGG CACCGCCAGGACTACGGAGCTGTCTTCCTCTGTGACCACAGGTTCGCCTTTGCCGACGCAAGAGCCCAAC TGCCCTCCTGGGTGCGTCCCCACGTCAGGGTGTATGACAACTTTGGCCATGTCATCCGAGACGTGGCCCA GTTCTTCCGTGTTGCCGAGCGAACTATGCCAGCGCCGGCCCCCCGGGCTACAGCACCCAGTGTGCGTGGA GAAGATGCTGTCAGCGAGGCCAAGTCGCCTGGCCCCTTCTTCTCCACCAGGAAAGCTAAGAGTCTGGACC TGCATGTCCCCAGCCTGAAGCAGAGGTCCTCAGGGTCACCAGCTGCCGGGGACCCCGAGAGTAGCCTGTG TGTGGAGTATGAGCAGGAGCCAGTTCCTGCCCGGCAGAGGCCCAGGGGGCTGCTGGCCGCCCTGGAGCAC AGCGAACAGCGGGCGGGGAGCCCTGGCGAGGAGCAGGCCCACAGCTGCTCCACCCTGTCCCTCCTGTCTG AGAAGAGGCCGGCAGAAGAACCGCGAGGAGGGAGGAAGAAGATCCGGCTGGTCAGCCACCCGGAGGAGCC CGTGGCTGGTGCACAGACGGACAGGGCCAAGCTCTTCATGGTGGCCGTGAAGCAGGAGTTGAGCCAAGCC AACTTTGCCACCTTCACCCAGGCCCTGCAGGACTACAAGGGTTCCGATGACTTCGCCGCCCTGGCCGCCT GTCTCGGCCCCCTCTTTGCTGAGGACCCCAAGAAGCACAACCTGCTCCAAGGCTTCTACCAGTTTGTGCG GCCCCACCATAAGCAGCAGTTTGAGGAGGTCTGTATCCAGCTGACAGGACGAGGCTGTGGCTATCGGCCT GAGCACAGCATTCCCCGAAGGCAGCGGGCACAGCCGGTCCTGGACCCCACTGGAAGAACGGCGCCGGATC CCAAGCTGACCGTGTCCACGGCTGCAGCCCAGCAGCTGGACCCCCAAGAGCACCTGAACCAGGGCAGGCC CCACCTGTCGCCCAGGCCACCCCCAACAGGAGACCCTGGCAGCCAACCACAGTGGGGGTCTGGAGTGCCC AGAGCAGGGAAGCAGGGCCAGCACGCCGTGAGCGCCTACCTGGCTGATGCCCGCAGGGCCCTGGGGTCCG CGGGCTGTAGCCAACTCTTGGCAGCGCTGACAGCCTATAAGCAAGACGACGACCTCGACAAGGTGCTGGC TGTGTTGGCCGCCCTGACCACTGCAAAGCCAGAGGACTTCCCCCTGCTGCACAGGTTCAGCATGTTTGTG CGTCCACACCACAAGCAGCGCTTCTCACAGACGTGCACAGACCTGACCGGCCGGCCCTACCCGGGCATGG AGCCACCGGGACCCCAGGAGGAGAGGCTTGCCGTGCCTCCTGTGCTTACCCACAGGGCTCCCCAACCAGG CCCCTCACGGTCCGAGAAGACCGGGAAGACCCAGAGCAAGATCTCGTCCTTCCTTAGACAGAGGCCAGCA GGGACTGTGGGGGCGGGCGGTGAGGATGCAGGTCCCAGCCAGTCCTCAGGACCTCCCCACGGGCCTGCAG CATCTGAGTGGGGTGAGCCTCATGGGAGAGACATCGCTGGGCAGCAGGCCACGGGAGCTCCGGGCGGGCC CCTCTCAGCAGGCTGTGTGTGCCAGGGCTGTGGGGCAGAGGACGTGGTGCCCTTCCAGTGCCCTGCCTGT GACTTCCAGCGCTGCCAAGCCTGCTGGCAACGGCACCTTCAGGCCTCTAGGATGTGCCCAGCCTGCCACA CCGCCTCCAGGAAGCAGAGCGTCATGCAGGTCTTCTGGCCAGAGCCCCAGTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001283009
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001283009.1, NP_001269938.1
RefSeq Size	5140 bp
RefSeq ORF	3903 bp
Locus ID	51750
UniProt ID	Q9NZ71
Protein Families	Druggable Genome
Gene Summary	This gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013] Transcript Variant: This variant (3) represents the longest transcript and encodes the longest protein (isoform 3).

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.