SLC24A1 (NM_001301033) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	CSNB1D; HsT17412; NCKX; NCKX1; RODX
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_001301033, the custom clone sequence may differ by one or more nucleotides ATGGGGAAATTGATCAGGATGGGGCCGCAAGAGAGGTGGTTACTCCGGACAAAGCGGCTTCATTGGAGTC GCCTCCTCTTCTTACTGGGAATGTTGATCATCGGTTCTACTTATCAGCACCTTAGGAGACCCCGGGGCCT TTCCTCATTGTGGGCAGCAGTCTCTTCTCATCAGCCTATAAAACTGGCCAGTCGGGACCTCTCCAGTGAA GAGATGATGATGATGAGCAGCAGCCCTTCAAAACCTAGCTCCGAAATGGGGGGTAAGATGCTGGTACCCC AAGCCTCAGTGGGCAGTGATGAAGCAACACTGAGCATGACAGTGGAGAATATCCCCAGTATGCCTAAAAG AACAGCCAAGATGATCCCAACAACAACCAAGAATAATTACAGCCCAACAGCAGCAGGTACAGAAAGAAGG AAGGAAGACACCCCAACATCCAGTAGAACACTGACTTACTACACCTCAACTTCAAGCAGACAAATAGTAA AAAAGTATACCCCAACACCCAGGGGAGAAATGAAGAGCTACAGCCCAACTCAAGTGAGGGAAAAGGTGAA GTATACTCCTTCCCCACGTGGTAGAAGAGTAGGCACTTACGTGCCGTCCACATTCATGACAATGGAAACA AGCCATGCGATCACCCCCAGGACAACAGTGAAAGACAGTGACATTACAGCAACCTATAAAATACTCGAAA CCAACTCTCTTAAGAGAATAATGGAGGAAACCACCCCAACCACTCTCAAGGGAATGTTTGATAGCACCCC AACTTTTCTGACACATGAGGTAGAAGCAAACGTCTTGACTTCTCCAAGGAGCGTCATGGAAAAAAACAAC CTGTTTCCCCCCAGAAGAGTGGAAAGTAACAGCTCAGCCCATCCCTGGGGGTTAGTGGGAAAGAGCAACC CGAAGACTCCCCAGGGAACAGTCCTGTTGCATACCCCAGCCACCTCTGAGGGGCAGGTGACAATAAGCAC CATGACAGGCAGCAGCCCAGCAGAAACCAAAGCCTTCACTGCTGCCTGGAGTCTTAGGAATCCTTCACCC AGGACCAGTGTATCAGCCATCAAAACAGCCCCAGCCATAGTCTGGAGGCTGGCAAAGAAACCTTCCACAG CACCCAGCACCTCAACAACCCCTACGGTCAGGGCAAAGCTGACCATGCAGGTCCATCACTGTGTGGTTGT GAAGCCAACCCCAGCCATGCTCACCACTCCCTCCCCAAGCCTCACAACAGCCCTGCTCCCAGAGGAGCTC AGTCCTAGTCCCTCAGTGCTGCCTCCCAGCTTGCCAGACCTCCACCCCAAGGGAGAGTACCCCCCAGATC TGTTCAGTGTGGAGGAGCGGCGGCAGGGCTGGGTGGTCCTGCACGTTTTTGGCATGATGTATGTGTTTGT GGCCTTGGCCATTGTTTGCGACGAGTACTTCGTTCCAGCCCTGGGTGTCATCACAGACAAGCTGCAGATC TCCGAGGATGTGGCAGGCGCCACATTCATGGCTGCTGGAGGCTCTGCTCCTGAGCTCTTCACCTCCCTCA TCGGTGTCTTCATTTCCCACAGCAACGTGGGCATTGGTACCATTGTGGGCTCTGCTGTGTTCAACATTCT CTTTGTCATTGGCACTTGTTCCCTCTTCTCCCGAGAGATCCTCAACCTCACCTGGTGGCCCTTATTCCGT GATGTCTCCTTCTACATCCTTGACCTGATAATGCTCATCCTCTTCTTCCTGGACAGCCTCATTGCCTGGT GGGAGAGCCTGCTGCTGCTGCTGGCCTATGCCTTCTATGTGTTCACCATGAAGTGGAACAAGCATATCGA GGTCTGGGTGAAGGAGCAGCTCAGCAGGAGGCCAGTGGCCAAGGTCATGGCCTTAGAAGACCTCAGCAAG CTCCCGTCCTTGCTGACCCGAGGGAGCAGCTCGACCTCTCTGCACAACAGCACCATCCGCAGCACCATCT ACCAGCTCATGCTCCACAGCCTGGACCCCCTGAGGGAAGTTCGCCTTGCCAAGGAGAAGGAGGAGGAGAG CTTGAATCAAGGGGCCAGAGCCCAACCCCAGGCCAAAGCAGAAAGCAAACCAGAAGAGGAGGAGCCAGCC AAGCTCCCTGCGGTCACGGTCACACCAGCCCCTGTTCCAGACATCAAGGGAGATCAGAAGGAGAATCCAG GCGGTCAGGAAGATGTGGCTGAGGCCGAGAGCACAGGTGAAATGCCAGGCGAAGAGGGCGAAACTGCTGG TGAAGGTGAAACTGAAGAGAAAAGTGGAGGTGAAACTCAACCAGAAGGTGAAGGTGAAACTGAAACACAA GGAAAAGGAGAAGAATGTGAAGATGAAAATGAAGCAGAAGGAAAAGGAGACAATGAAGGTGAAGATGAGG GTGAAATCCACGCAGAAGATGGTGAAATGAAAGGTAATGAAGGTGAAACTGAAAGCCAGGAACTCAGTGC TGAAAATCACGGTGAAGCCAAAAATGATGAGAAAGGTGTAGAAGATGGAGGGGGAAGTGATGGAGGGGAT AGCGAAGAGGAGGAAGAGGAGGAGGAAGAGCAGGAGGAAGAGGAGGAGGAGGAAGAGCAGGAGGAAGAGG AGGAGGAGGAGGAGGAAGAGGAGGAGAAGGGAAATGAAGAGCCTCTGTCCCTGGACTGGCCTGAAACCAG GCAGAAGCAGGCCATTTACCTCTTCCTTCTGCCCATCGTGTTCCCACTGTGGCTGACAGTCCCCGACGTC CGAAGGCAGGAGTCTAGGAAGTTTTTTGTTTTCACCTTCCTGGGATCTATCATGTGGATAGCCATGTTCT CATACCTCATGGTGTGGTGGGCTCACCAGGTTGGTGAAACAATAGGGATTTCTGAAGAGATCATGGGCCT GACAATCCTTGCAGCAGGCACATCAATTCCTGACCTCATCACCAGTGTGATTGTCGCTCGAAAAGGCCTG GGAGACATGGCTGTGTCAAGCTCTGTGGGCAGTAACATATTTGATATCACTGTGGGAGTTGGAAGCTGTG AAATGTTTCAGCATGGTGCTATTCACTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001301033
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001301033.1, NP_001287962.1
RefSeq Size	3906 bp
RefSeq ORF	3039 bp
Locus ID	9187
UniProt ID	O60721
Protein Families	Druggable Genome, Transmembrane
Gene Summary	This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. The encoded protein plays an important role in sodium/calcium exchange in retinal rod and cone photoreceptors by mediating the extrusion of one calcium ion and one potassium ion in exchange for four sodium ions. Mutations in this gene may play a role in congenital stationary night blindness. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] Transcript Variant: This variant (5) differs in the 5' UTR, lacks an alternate in-frame exon in the central coding region, and contains alternate 3' exon structure and thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (5) has a distinct C-terminus and is shorter than isoform 1.

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.