SRRM1 (NM_001303448) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	160-KD; POP101; SRM160
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_001303448, the custom clone sequence may differ by one or more nucleotides ATGGACGCGGGATTTTTCCGCGGAACAAGTGCAGAACAGGATAATCGGTTCAGCAACAAACAGAAGAAAC TACTGAAGCAGCTGAAATTTGCAGAATGCCTAGAAAAAAAGGTGGACATGAGCAAAGTAAATTTGGAGGT TATAAAGCCTTGGATAACAAAAAGAGTAACGGAAATCCTTGGGTTTGAAGATGATGTTGTGATTGAGTTT ATATTCAACCAGCTGGAAGTGAAGAATCCAGACTCCAAAATGATGCAAATCAACCTGACTGGATTTTTGA ATGGAAAAAATGCTCGAGAATTTATGGGAGAACTGTGGCCCCTGCTGCTAAGTGCACAAGAAAACATCGC GGGAATCCCTTCTGCTTTCCTAGAACTGAAGAAAGAAGAAATAAAACAAAGACAGATTGAACAAGAAAAA CTGGCATCTATGAAAAAGCAAGATGAAGACAAAGATAAAAGAGATAAGGAAGAAAAAGAAAGCAGCAGAG AAAAAAGGGAGCGGTCTCGTAGCCCAAGAAGACGCAAATCCAGATCTCCTTCCCCTAGAAGACGATCTTC CCCTGTCAGGAGAGAGAGAAAGCGCAGTCATTCTCGATCTCCCCGTCACAGAACCAAGAGCCGGAGTCCT TCCCCTGCTCCAGAAAAGAAGGAAAAAACTCCAGAGCTCCCAGAACCTTCAGTGAAAGTAAAAGAACCTT CAGTACAAGAGGCTACTTCTACTAGTGACATTCTGAAAGTTCCCAAACCTGAACCTATACCAGAGCCTAA AGAACCTTCTCCGGAAAAAAATTCCAAAAAAGAAAAGGAGAAGGAGAAGACCCGACCACGATCTCGGTCA CGCTCCAAATCAAGATCCCGGACGCGGTCCCGCTCTCCTTCTCACACTCGACCTAGACGGCGCCATAGAT CCCGATCAAGATCGTATTCACCTAGAAGGCGGCCAAGCCCAAGAAGGCGGCCATCTCCTCGAAGAAGAAC TCCGCCAAGAAGAATGCCTCCTCCACCAAGGCATAGAAGGAGTAGATCTCCAGTAAGACGAAGAAGACGT TCGTCAGCATCCTTGTCTGGGAGTAGCTCATCATCCTCTTCATCTCGTTCACGGTCACCACCAAAGAAGC CTCCCAAGAGGACATCCAGCCCCCCTCGGAAAACTCGTAGGTTATCTCCTTCAGCAAGTCCTCCAAGGCG AAGGCACAGGCCATCACCTCCTGCAACTCCACCACCCAAAACTCGGCATTCCCCTACACCCCAGCAGTCA AACCGTACAAGAAAAAGTCGTGTTTCTGTGTCTCCAGGGAGAACTTCAGTGACAAAACATAAAGGTACTG AGAAAAGAGAATCCCCTTCACCAGCACCGAAGCCTAGAAAAGTAGAGTTATCTGAATCGGAAGAAGATAA AGGTGGCAAAATGGCTGCAGCAGATTCTGTGCAGCAGAGACGCCAATACAGACGACAAAACCAGCAGTCT TCATCTGACTCTGGCTCCTCCTCCTCCTCAGAAGATGAACGACCCAAGAGATCCCATGTGAAGAATGGTG AGGTTGGCAGGCGGCGGAGACATTCCCCTTCCCGGAGTGCTTCTCCATCACCACGAAAGCGCCAAAAAGA GACTTCCCCTCGGATGCAGATGGGAAAGCGATGGCAATCGCCAGTGACTAAAAGTGGTAGACGGAGGAGA AGTCCATCCCCACCACCCACCAGAAGGCGACGGTCTCCTTCTCCCGCCCCTCCTCCTCGACGGCGCAGGA CTCCCACACCACCACCACGACGAAGGACTCCTTCTCCTCCCCCACGTCGGCGCTCACCTTCTCCTAGAAG ATACTCTCCTCCAATACAGAGGAGATACTCTCCTTCTCCACCTCCAAAGAGAAGAACGGCTTCACCTCCT CCCCCTCCTAAACGAAGAGCATCACCATCTCCACCACCAAAGCGGCGGGTCTCCCATTCTCCACCTCCCA AACAAAGAAGCTCCCCAGTCACCAAGAGACGTTCACCTTCATTATCATCCAAGCATAGGAAAGGGTCTTC CCCAAGCCGCTCTACCCGGGAGGCCCGATCACCACAACCAAACAAACGGCATTCGCCCTCACCACGGCCT CGAGCTCCTCAGACCTCCTCAAGTCCTCCACCCGTTCGAAGAGGAGCGTCGTCATCACCCCAAAGAAGGC AGTCCCCGTCTCCAAGTACTAGGCCCATTAGGAGAGTCTCCAGGACTCCGGAACCTAAAAAGATAAAAAA GGCTGCTTCCCCAAGCCCACAGTCTGTAAGAAGGGTCTCATCCTCCCGATCTGTCTCCGGGTCTCCTGAG CCAGCAGCTAAAAAGCCCCCAGCACCTCCATCCCCCGTCCAGTCTCAGTCACCGTCTACAAACTGGTCAC CAGCTGTACCGGTCAAAAAGGCCAAAAGCCCAACACCGAGCCCATCACCGCCAAGAAATTCAGATCAGGA AGGAGGTGGAAAGAAAAAGAAGAAAAAGAAGGACAAGAAACACAAAAAGGATAAGAAGCACAAGAAGCAC AAAAAACACAAGAAGGAAAAGGCTGTGGCTGCAGCTGCTGCAGCTGCTGTGACCCCTGCAGCCATTGCAG CTGCCACAACCACATTAGCACAGGAAGAGCCAGTGGCAGCGCCAGAGCCGAAGAAGGAGACTGAAAGTGA AGCTGAAGATAACCTTGATGATTTAGAAAAGCACCTGCGTGAAAAGGCCCTGAGATCAATGAGGAAGGCC CAAGTGTCCCCACAGTCTTAG
Restriction Sites	SgfI-MluI
ACCN	NM_001303448
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001303448.1, NP_001290377.1
RefSeq Size	3988 bp
RefSeq ORF	2751 bp
Locus ID	10250
UniProt ID	Q8IYB3
Gene Summary	Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.