SEMCAP3 (PDZRN3) (NM_001303140) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	LNX3; SEMACAP3; SEMCAP3
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_001303140, the custom clone sequence may differ by one or more nucleotides ATGTTCACGCCTCCATCAGAGTCTCAGCTGGTGGACACGGGAACCCAAACCGACATCACCTTTGAACATA TCATGGCCCTCACTAAGATGTCCTCTCCCAGCCCACCCGTGCTGGATCCCTATCTCTTGCCAGAGGAGCA TCCCTCAGCCCATGAATACTACGATCCAAATGACTACATTGGAGACATCCATCAGGAGATGGACAGGGAG GAGCTGGAGCTGGAGGAAGTGGACCTCTACAGAATGAACAGCCAGGACAAGCTGGGCCTCACTGTGTGCT ACCGGACGGACGATGAAGACGACATTGGGATTTATATCAGTGAGATTGACCCTAACAGCATTGCAGCCAA GGATGGGCGCATCCGAGAAGGAGACCGCATTATCCAGATTAATGGGATAGAGGTGCAGAACCGTGAAGAG GCTGTGGCTCTTCTAACCAGTGAAGAAAATAAAAACTTTTCATTGCTGATTGCAAGGCCTGAACTCCAGC TGGATGAGGGCTGGATGGATGATGACAGGAACGACTTTCTGGATGACCTGCACATGGACATGCTGGAGGA GCAGCACCACCAGGCCATGCAATTCACAGCTAGCGTGCTGCAGCAGAAGAAGCACGACGAAGACGGTGGG ACCACAGATACAGCCACCATCTTGTCCAACCAGCACGAGAAGGACAGCGGTGTGGGGCGGACCGACGAGA GCACCCGTAATGACGAGAGCTCGGAGCAAGAGAACAATGGCGACGACGCCACCGCATCCTCCAACCCGCT GGCGGGGCAGAGGAAGCTCACCTGCAGCCAGGACACCTTGGGCAGCGGCGACCTGCCCTTCAGCAACGAG TCTTTCATTTCGGCCGACTGCACGGACGCCGACTACCTGGGGATCCCGGTGGACGAGTGCGAGCGCTTCC GCGAGCTCCTGGAGCTCAAGTGCCAGGTGAAGAGCGCCACCCCTTACGGCCTGTACTACCCTAGCGGCCC CCTGGACGCCGGCAAGAGTGACCCTGAGAGCGTGGACAAGGAGCTGGAGCTGCTGAACGAAGAGCTGCGC AGCATCGAGCTGGAGTGCCTGAGCATCGTGCGCGCCCACAAGATGCAGCAGCTCAAGGAGCAGTACCGCG AGTCCTGGATGCTGCACAACAGCGGCTTCCGCAACTACAACACCAGCATCGACGTGCGCAGACACGAGCT CTCAGATATCACCGAGCTCCCGGAGAAATCCGACAAGGACAGCTCGAGCGCCTACAACACAGGCGAGAGC TGCCGCAGCACCCCGCTCACCCTGGAGATCTCCCCCGACAACTCCTTGAGGAGAGCGGCGGAGGGCATCA GCTGCCCGAGCAGCGAAGGGGCTGTGGGGACCACGGAAGCCTACGGGCCAGCCTCCAAGAATCTGCTCTC CATCACGGAAGATCCCGAAGTGGGCACCCCTACCTATAGCCCGTCCCTGAAGGAGCTGGACCCCAACCAG CCCCTGGAAAGCAAAGAGCGGAGAGCCAGCGACGGGAGCCGGAGCCCCACGCCCAGCCAGAAGCTGGGCA GCGCCTACCTGCCCTCCTATCACCACTCCCCATACAAGCACGCGCACATCCCGGCGCACGCCCAGCACTA CCAGAGCTACATGCAGCTGATCCAGCAGAAGTCGGCCGTGGAGTACGCGCAAAGCCAGATGAGCCTGGTG AGCATGTGCAAGGACCTGAGCTCTCCCACCCCGTCGGAGCCGCGCATGGAGTGGAAGGTGAAGATCCGCA GCGACGGGACGCGCTACATCACCAAGAGGCCCGTGCGGGACCGCCTGCTGCGGGAGCGCGCCCTGAAGAT CCGGGAAGAGCGCAGCGGCATGACCACCGACGACGACGCGGTGAGCGAGATGAAGATGGGGCGCTACTGG AGCAAGGAGGAGAGGAAGCAGCACCTGGTGAAGGCCAAGGAGCAGCGGCGGCGGCGCGAGTTCATGATGC AGAGCAGGTTGGATTGTCTCAAGGAGCAGCAAGCAGCCGATGACAGGAAGGAGATGAACATTCTCGAACT GAGCCACAAAAAGATGATGAAGAAGAGGAATAAGAAAATCTTCGATAACTGGATGACGATCCAAGAACTC TTAACCCACGGCACAAAATCCCCGGACGGCACTAGAGTATACAATTCCTTCCTATCGGTGACTACTGTAT AA
Restriction Sites	SgfI-MluI
ACCN	NM_001303140
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001303140.1, NP_001290069.1
RefSeq Size	3458 bp
RefSeq ORF	2172 bp
Locus ID	23024
UniProt ID	Q9UPQ7
Protein Families	Druggable Genome
Gene Summary	This gene encodes a member of the LNX (Ligand of Numb Protein-X) family of RING-type ubiquitin E3 ligases. This protein may function in vascular morphogenesis and the differentiation of adipocytes, osteoblasts and myoblasts. This protein may be targeted for degradation by the human papilloma virus E6 protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] Transcript Variant: This variant (3) lacks several exons and uses an alternate 5' terminal exon, compared to variant 1. These differences result in a distinct 5' UTR and cause translation initiation at an in-frame downstream start codon, compared to variant 1. The resulting protein (isoform 3) has a shorter N-terminus compared to isoform 1.

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