TECPR2 (NM_001172631) Human Untagged Clone
CAT＃: SC329325
TECPR2 (untagged)-Human tectonin beta-propeller repeat containing 2 (TECPR2) transcript variant 2
CNY 10450.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | KIAA0329; SPG49 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC329325 representing NM_001172631.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCATCGATATCAGAGCCTGTTACATTCAGAGAGTTCTGCCCGTTGTACTATCTCCTCAATGCCATT CCGACAAAGATCCAGAAGGGTTTCCGCTCTATCGTGGTCTATCTCACGGCCCTCGACACCAACGGGGAC TACATCGCGGTGGGCAGCAGCATCGGCATGCTCTATCTGTACTGCCGGCACCTCAACCAGATGAGGAAG TACAACTTTGAGGGGAAGACGGAATCTATCACTGTGGTGAAGCTGCTGAGCTGCTTTGATGACCTGGTG GCAGCAGGCACAGCCTCTGGCAGGGTTGCAGTTTTTCAACTTGTATCTTCATTGCCAGGGAGAAATAAA CAGCTTCGGAGATTTGATGTCACTGGTATTCACAAAAATAGCATTACAGCTCTGGCTTGGAGCCCCAAT GGAATGAAATTGTTCTCTGGAGATGACAAAGGCAAAATTGTTTATTCTTCTCTGGATCTAGACCAGGGG CTCTGTAACTCCCAGCTGGTGTTGGAGGAGCCATCTTCCATTGTGCAGCTGGATTATAGCCAGAAAGTG CTGCTGGTCTCTACTCTGCAAAGAAGTCTGCTCTTTTACACTGAAGAAAAGTCTGTAAGGCAAATTGGA ACACAACCAAGGAAAAGTACTGGGAAATTTGGTGCTTGTTTTATACCAGGACTCTGTAAGCAAAGTGAT CTAACCTTGTATGCGTCACGGCCCGGGCTCCGGCTATGGAAGGCTGATGTCCACGGGACTGTTCAAGCC ACGTTTATCTTAAAAGATGCTTTTGCCGGGGGAGTCAAGCCTTTTGAACTGCACCCGCGTCTGGAATCC CCCAACAGTGGAAGTTGCAGCTTACCTGAGAGGCACCTGGGGCTTGTTTCATGTTTCTTTCAAGAAGGC TGGGTGCTGAGTTGGAATGAATATAGTATCTATCTCCTAGACACAGTCAACCAGGCCACAGTTGCTGGT TTGGAAGGATCCGGTGATATTGTGTCTGTTTCGTGCACAGAAAATGAAATATTTTTCTTGAAAGGAGAT AGGAACATTATAAGAATTTCAAGCAGGCCTGAAGGATTAACATCAACAGTGAGAGATGGTCTGGAGATG TCTGGATGCTCAGAGCGTGTCCACGTGCAGCAAGCGGAGAAGCTGCCAGGGGCCACAGTTTCTGAGACG AGGCTCAGAGGCTCTTCCATGGCCAGCTCCGTGGCCAGCGAGCCAAGGAGCAGGAGCAGCTCGCTCAAC TCCACCGACAGCGGCTCCGGGCTCCTGCCCCCTGGGCTCCAGGCCACCCCTGAGCTGGGCAAGGGCAGC CAGCCCCTGTCACAGAGATTCAACGCCATCAGCTCAGAGGACTTTGACCAGGAGCTTGTCGTGAAGCCT ATCAAAGTGAAAAGGAAGAAGAAGAAGAAGAAGACAGAAGGTGGAAGCAGGAGCACCTGTCACAGCTCC CTGGAATCGACACCCTGCTCCGAATTTCCTGGGGACAGTCCCCAGTCCTTGAACACAGACTTGCTGTCG ATGACCTCAAGTGTCCTGGGCAGTAGCGTGGATCAGTTAAGTGCAGAGTCTCCAGACCAGGAAAGCAGC TTCAATGGTGAAGTGAACGGTGTCCCACAGGAAAATACTGACCCCGAAACGTTTAATGTCCTGGAGGTG TCAGGATCAATGCCTGATTCTCTGGCTGAGGAAGATGACATTAGAACTGAAATGCCACACTGTCACCAT GCACATGGGCGGGAGCTGCTCAATGGAGCGAGGGAAGATGTGGGAGGCAGTGATGTCACGGGACTCGGA GATGAGCCGTGTCCTGCAGATGATGGACCAAATAGCACACAGTTACCCTTCCAAGAACAGGACAGCTCT CCTGGGGCGCATGATGGGGAAGACATCCAACCCATTGGCCCCCAAAGCACTTTTTGTGAAGTCCCCCTC CTGAACTCACTCACTGTGCCTTCCAGCCTCAGCTGGGCCCCAAGTGCTGAACAGTGGCTGCCTGGGACC AGAGCTGATGAAGGCAGCCCCGTGGAGCCCAGCCAAGAGCAGGACATCCTAACCAGCATGGAGGCCTCT GGCCACCTCAGCACAAATCTCTGGCATGCTGTCACTGATGATGACACAGGTCAGAAAGAAATACCCATT TCTGAACGTGTCTTGGGGAGTGTGGGAGGACAGCTGACTCCGGTCTCTGCCTTGGCAGCCAGCACTCAC AAGCCCTGGCTTGAGCAGCCTCCACGGGATCAGACATTGACGTCCAGCGATGAGGAGGACATCTATGCC CACGGGCTTCCTTCTTCATCCTCAGAGACGAGTGTGACAGAGCTCGGACCTAGTTGCTCCCAGCAGGAC CTGAGCCGGCTGGGTGCAGAGGACGCCGGGCTGCTCAAGCCAGATCAGTTTGCAGAAAGCTGGATGGGC TACTCGGGTCCCGGCTATGGCATCCTCAGCTTGGTGGTCTCCGAGAAGTATATCTGGTGCCTGGACTAC AAAGGCGGCCTGTTCTGCAGCGCGTTGCCGGGCGCCGGGCTGCGCTGGCAGAAGTTTGAAGATGCTGTC CAGCAGGTGGCAGTCTCGCCCTCAGGAGCCCTTCTCTGGAAGATTGAACAGAAATCTAACCGGGCTTTT GCTTGTGGGAAAGTCACCATCAAGGGGAAGCGGCACTGGTACGAAGCCCTGCCCCAGGCAGTGTTTGTG GCCCTGAGCGATGACACGGCCTGGATCATCAGGACCAGTGGGGACCTATACTTGCAGACAGGTCTGAGC GTGGATCGCCCTTGTGCCAGAGCCGTAAAGGTGGACTGTCCCTACCCGCTGTCCCAGATCACAGCCCGG AACAATGTGGTGTGGGCGCTGACAGAGCAGAGGGCCCTCCTGTACCGGGAGGGCGTGAGCAGCTTCTGT CCGGAAGGCGAGCAGTGGAAGTGTGACATTGTCAGCGAAAGGCAAGCTTTAGAACCCGTCTGCATAACG CTCGGGGATCAGCAGACTCTCTGGGCCCTGGACATCCATGGGAACCTGTGGTTCAGAACTGGCATTATT TCCAAGAAGCCCCAAGGAGATGACGACCATTGGTGGCAAGTGAGCATCACGGACTATGTGGTGTTTGAC CAGTGCAGCTTATTTCAGACGATAATCCATGCCACTCACTCGGTGGCCACAGCAGCCCAAGCCCCCGTA GAAAAGGTGGCAGATAAGCTGCGCATGGCGTTTTGGTCCCAGCAGCTTCAGTGCCAGCCAAGCCTTCTC GGGGTCAATAACAGCGGTGTCTGGATCTCCTCGGGCAAGAATGAATTCCACGTCGCTAAGGGAAGTCTC ATAGGCACCTACTGGAATCATGTGGTTCCCCGTGGGACAGCTTCTGCTACAAAATGGGCCTTTGTGTTG GCTTCTGCAGCTCCCACGAAGGAAGGAAGCTTCCTGTGGCTGTGCCAGAGCAGCAAGGACCTGTGCAGC GTCAGCGCCCAGAGCGCACAGTCGCGGCCCTCCACGGTGCAGCTGCCTCCCGAAGCCGAGATGCGCGCC TATGCCGCCTGCCAGGATGCGCTGTGGGCGCTGGACAGCCTCGGCCAGGTGTTCATCAGGACGCTCTCC AAGAGCTGCCCCACGGGCATGCACTGGACCAGGCTGGACCTCTCCCAGCTAGGAGCTGTAAAATTGACA AGCTTGGCATGTGGAAATCAGCACATCTGGGCCTGTGATTCCAGGGGTGGAGTTTACTTCCGTGTAGGG ACTCAGCCTCTCAATCCCAGTCTCATGCTTCCAGCCTGGATAATGATTGAGCCACCTGTCCAGGTAAGC AGAAGTTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001172631 |
| Insert Size | 3804 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001172631.2 |
| RefSeq Size | 4478 bp |
| RefSeq ORF | 3804 bp |
| Locus ID | 9895 |
| UniProt ID | O15040 |
| MW | 137.9 kDa |
| Gene Summary | The protein encoded by this gene is a member of the tectonin beta-propeller repeat-containing (TECPR) family, and contains both TECPR and tryptophan-aspartic acid repeat (WD repeat) domains. This gene has been implicated in autophagy, as reduced expression levels of this gene have been associated with impaired autophagy. Recessive mutations in this gene have been associated with a hereditary form of spastic paraparesis (HSP). HSP is characterized by progressive spasticity and paralysis of the legs. There is also some evidence linking mutations in this gene with birdshot chorioretinopathy (BSCR), which results in inflammation of the choroid and retina. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015] Transcript Variant: This variant (2) represents use of an alternate 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, compared to isoform 1. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC230687 | TECPR2 (Myc-DDK-tagged)-Human tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 2 |
CNY 8824.00 |
|
| RC230687L3 | Lenti-ORF clone of TECPR2 (Myc-DDK-tagged)-Human tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 2 |
CNY 14540.00 |
|
| RC230687L4 | Lenti-ORF clone of TECPR2 (mGFP-tagged)-Human tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 2 |
CNY 14540.00 |
|
| RG230687 | TECPR2 (tGFP-tagged) - Human tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 2 |
CNY 13870.00 |
