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NOTUM (NM_178493) Human Untagged Clone
CAT＃: SC327883
NOTUM (untagged)-Human notum pectinacetylesterase homolog (Drosophila) (NOTUM)
CNY 5,856.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | hNOTUM |
| Vector | PCMV6-Neo |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>NCBI ORF sequence for NM_178493, the custom clone sequence may differ by one or more nucleotides
ATGGGCCGAGGGGTGCGCGTGCTGCTGCTGCTGAGCCTGCTGCACTGCGCCGGGGGCAGC GAGGGCAGGAAGACCTGGCGGCGCCGGGGTCAGCAGCCGCCTCCTCCCCCGCGGACCGAG GCGGCGCCGGCGGCCGGACAGCCCGTGGAGAGCTTCCCGCTGGACTTCACGGCCGTGGAG GGTAACATGGACAGCTTCATGGCGCAAGTCAAGAGCCTGGCGCAGTCCCTGTACCCCTGC TCCGCGCAGCAGCTCAACGAGGACCTGCGCCTGCACCTCCTACTCAACACCTCGGTGACC TGCAACGACGGCAGCCCCGCCGGCTACTACCTGAAGGAGTCCAGGGGCAGCCGGCGGTGG CTCCTCTTCCTGGAAGGCGGCTGGTACTGCTTCAACCGCGAGAACTGCGACTCCAGATAC GACACCATGCGGCGCCTCATGAGCTCCCGGGACTGGCCGCGCACTCGCACAGGCACAGGG ATCCTGTCCTCACAGCCGGAGGAGAACCCCTACTGGTGGAACGCAAACATGGTCTTCATC CCCTACTGCTCCAGTGATGTTTGGAGCGGGGCTTCATCCAAGTCTGAGAAGAACGAGTAC GCCTTCATGGGCGCCCTCATCATCCAGGAGGTGGTGCGGGAGCTTCTGGGCAGAGGGCTG AGCGGGGCCAAGGTGCTGCTGCTGGCCGGGAGCAGCGCGGGGGGCACCGGGGTGCTCCTG AATGTGGACCGTGTGGCTGAGCAGCTGGAGAAGCTGGGCTACCCAGCCATCCAGGTGCGA GGCCTGGCTGACTCCGGCTGGTTCCTGGACAACAAGCAGTATCGCCACACAGACTGCGTC GACACGATCACGTGCGCGCCCACGGAGGCCATCCGCCGTGGCATCAGGTACTGGAACGGG GTGGTCCCGGAGCGCTGCCGACGCCAGTTCCAGGAGGGCGAGGAGTGGAACTGCTTCTTT GGCTACAAGGTCTACCCGACCCTGCGCTGCCCTGTGTTCGTGGTGCAGTGGCTGTTTGAC GAGGCACAGCTGACGGTGGACAACGTGCACCTGACGGGGCAGCCGGTGCAGGAGGGCCTG CGGCTGTACATCCAGAACCTCGGCCGCGAGCTGCGCCACACACTCAAGGACGTGCCGGCC AGCTTTGCCCCCGCCTGCCTCTCCCATGAGATCATCATCCGGAGCCACTGGACGGATGTC CAGGTGAAGGGGACGTCGCTGCCCCGAGCACTGCACTGCTGGGACAGGAGCCTCCATGAC AGCCACAAGGCCAGCAAGACCCCCCTCAAGGGCTGCCCCGTCCACCTGGTGGACAGCTGC CCCTGGCCCCACTGCAACCCCTCATGCCCCACCGTCCGAGACCAGTTCACGGGGCAAGAG ATGAACGTGGCCCAGTTCCTCATGCACATGGGCTTCGACATGCAGACGGTGGCCCAGCCG CAGGGACTGGAGCCCAGTGAGCTGCTGGGGATGCTGAGCAACGGAAGC |
| Restriction Sites | Please inquire |
| ACCN | NM_178493 |
| Insert Size | 2281 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_178493.5, NP_848588.3 |
| RefSeq Size | 2281 bp |
| RefSeq ORF | 1491 bp |
| Locus ID | 147111 |
| UniProt ID | Q6P988 |
| Gene Summary | Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors (PubMed:25731175).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209331 | NOTUM (Myc-DDK-tagged)-Human notum pectinacetylesterase homolog (Drosophila) (NOTUM) |
CNY 5,488.00 |
|
| RC209331L1 | Lenti ORF clone of Human notum pectinacetylesterase homolog (Drosophila) (NOTUM), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC209331L2 | Lenti ORF clone of Human notum pectinacetylesterase homolog (Drosophila) (NOTUM), mGFP tagged |
CNY 5,890.00 |
|
| RC209331L3 | Lenti ORF clone of Human notum pectinacetylesterase homolog (Drosophila) (NOTUM), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC209331L4 | Lenti ORF clone of Human notum pectinacetylesterase homolog (Drosophila) (NOTUM), mGFP tagged |
CNY 5,890.00 |
|
| RG209331 | NOTUM (tGFP-tagged) - Human notum pectinacetylesterase homolog (Drosophila) (NOTUM) |
CNY 7,088.00 |
|
| SC111889 | NOTUM (untagged)-Human notum pectinacetylesterase homolog (Drosophila) (NOTUM) |
CNY 7,220.00 |
