EFCAB4B (CRACR2A) (NM_001144958) Human Untagged Clone
CAT＃: SC326203
EFCAB4B (untagged)-Human EF-hand calcium binding domain 4B (EFCAB4B), transcript variant 1
CNY 5360.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EFCAB4B |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001144958 edited
AAGTCACCAGTGGCCAAAGTACCCTCCAGGTGTGAAGAGTTGCAGGTCCTCCGAGGAGCC GGGAGCTGCAAGGTTCTGAAAAAGACTTCAAGAAACTGACTAATCGCGATGGCTGCCCCT GACGGGAGGGTAGTCTCCAGACCCCAGAGACTTGGTCAGGGGTCTGGCCAGGGGCCAAAG GGGAGTGGAGCCTGCCTGCATCCCCTGGACAGCCTGGAGCAGAAGGAGACTCAGGAGCAA ACGTCGGGCCAGCTAGTCATGCTGAGGAAGGCACAGGAGTTCTTTCAGACCTGTGATGCT GAAGGCAAGGGCTTCATCGCCAGGAAGGATATGCAGAGGCTGCATAAGGAGCTACCGCTC AGCCTGGAGGAACTGGAGGATGTGTTTGATGCCCTGGATGCTGATGGCAATGGCTATCTG ACCCCACAGGAGTTCACTACTGGATTTAGTCACTTCTTCTTCAGCCAGAATAACCCAAGT CAGGAAGATGCAGGTGAACAGGTGGCCCAGCGCCATGAAGAGAAGGTGTATCTGTCCAGA GGGGATGAGGATCTGGGCGACATGGGCGAAGATGAGGAAGCCCAGTTCCGGATGCTGATG GACAGACTTGGAGCCCAAAAGGTGTTGGAAGATGAAAGTGATGTCAAGCAGCTCTGGTTG CAGCTGAAGAAGGAGGAACCTCATTTACTGTCCAACTTTGAAGACTTCCTGACCAGAATC ATCTCCCAGCTCCAAGAAGCCCATGAGGAGAAGAATGAACTGGAGTGTGCCCTAAAAAGG AAAATTGCTGCTTATGATGAAGAAATCCAGCATCTCTATGAGGAGATGGAACAACAAATC AAAAGTGAGAAGGAGCAGTTTCTCCTGAAGGACACAGAGAGGTTTCAAGCCCGCAGTCAA GAGCTGGAGCAGAAACTGTTATGTAAGGAGCAGGAGCTGGAGCAGCTCACCCAGAAGCAG AAAAGGCTGGAAGGTCAGTGCACAGCCCTGCATCATGACAAGCATGAGACCAAGGCTGAG AATACCAAGCTGAAACTCACTAACCAGGAGCTGGCCCGGGAGCTGGAGCGGACTTCCTGG GAGCTCCAGGATGCTCAGCAGCAGTTGGAAAGCCTCCAGCAAGAGGCCTGCAAACTCCAC CAAGAGAAGGAGATGGAAGTGTACCGTGTGACGGAGAGTCTACAGCGTGAGAAGGCCGGG CTCCTCAAGCAGCTGGATTTCCTAAGGGAAAGGAACAAGCACCTTCGGGATGAACGGGAC ATATGTTTTCAGAAAAATAAGGCAGCCAAGGCAAACACAGCTGCTTCCAGGGCAAGTTGG AAAAAGAGATCTGGCTCTGTGATAGGCAAATATGTGGACAGCAGAGGGATTCTTAGGAGC CAGTCAGAGGAGGAGGAGGAGGTGTTTGGCATCCCAAGGAGAAGCTCCCTGGGCCTGAGT GGATATCCCCTAACAGAAGAGGAGCCAGGAACCGGGGAGCCAGGGCCTGGGGGTCCGTAC CCCCGGCCGCTCCGCAGAATCATCTCCGTTGAAGAAGACCCCCTGCCCCAGCTCCTGGAT GGTGGCTTTGAGCAACCCCTGAGCAAATGCTCAGAAGAGGAAGAGGTCTCTGACCAGGGG GTACAGGGACAAATCCCGGAGGCCCCACCCTTGAAACTCACCCCCACATCCCCCCGAGGG CAGCCTGTTGGAAAAGAAGCCCTGTGTAAGGAGGAAAGCTCTCCCTCTGCCCCTGACCGG CTCTTCAAGATTGTGTTCGTGGGCAATTCCGCGGTGGGGAAGACATCCTTCCTGAGGAGA TTCTGTGAGGACCGGTTCTCCCCAGGCATGGCGGCCACTGTGGGCATTGATTACCGTGTG AAGACGTTGAATGTGGACAACTCTCAGGTGGCCCTGCAGCTGTGGGACACGGCTGGGCAG GAGAGGTACCGGTGCATCACCCAGCAGTTCTTCAGAAAGGCAGATGGTGTCATCGTCATG TACGATCTCACAGACAAGCAGTCGTTCCTGTCGGTCCGGCGGTGGCTGAGCAGCGTGGAG GAAGCTGTGGGAGACCGGGTGCCTGTTCTTCTGCTGGGTAATAAGCTTGACAACGAGAAG GAGCGGGAAGTCCCCCGGGGCCTCGGAGAGCAGCTTGCCACGGAGAACAATCTGATCTTC TATGAATGCAGCGCCTACTCTGGTCACAACACCAAAGAGTCCCTGCTCCATCTGGCCAGG TTCCTCAAGGAGCAAGAAGACACAGTGAGAGAGGACACCATTCAGGTCGGCCACCCTGCT AAGAAGAAATCCTGCTGTGGCTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_001144958 |
| Insert Size | 2300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001144958.1. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001144958.1, NP_001138430.1 |
| RefSeq Size | 2795 bp |
| RefSeq ORF | 2196 bp |
| Locus ID | 84766 |
| UniProt ID | Q9BSW2 |
| Gene Summary | Ca(2+)-binding protein that plays a key role in store-operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca(2+) concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca(2+) resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC226784 | EFCAB4B (Myc-DDK-tagged)-Human EF-hand calcium binding domain 4B (EFCAB4B), transcript variant 1 |
CNY 7320.00 |
|
| RC226784L3 | Lenti-ORF clone of EFCAB4B (Myc-DDK-tagged)-Human EF-hand calcium binding domain 4B (EFCAB4B), transcript variant 1 |
CNY 9220.00 |
|
| RC226784L4 | Lenti-ORF clone of EFCAB4B (mGFP-tagged)-Human EF-hand calcium binding domain 4B (EFCAB4B), transcript variant 1 |
CNY 9220.00 |
|
| RG226784 | EFCAB4B (tGFP-tagged) - Human EF-hand calcium binding domain 4B (EFCAB4B), transcript variant 1 |
CNY 8080.00 |
其它EFCAB4B产品
