MyoGEF (PLEKHG6) (NM_001144856) Human Untagged Clone
CAT＃: SC325332
PLEKHG6 (untagged)-Human pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (PLEKHG6), transcript variant 2
CNY 7220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MyoGEF |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001144856, the custom clone sequence may differ by one or more nucleotides
ATGAAGGCCTTTGGTCCTCCACATGAGGGCCCCCTCCAAGGACTCGTGGCCTCCCGCATT GAGACTTATGGGGGCCGGCATCGAGCCTCTGCTCAGAGCACTGCTGGCAGACTCTATCCC CGAGGATACCCTGTGCTGGATCCCAGTCGCCGACGCCTCCAGCAGTATGTCCCCTTTGCC AGGGGTTCTGGCCAGGCCCGAGGCCTGTCACCCATGAGACTGCGAGATCCAGAGCCCGAG AAGAGGCACGGGGGCCATGTGGGGGCTGGCCTGCTTCACTCCCCCAAACTCAAGGAACTC ACCAAGGCCCATGAGCTGGAGGTGAGGCTGCACACTTTCAGCATGTTTGGGATGCCCCGG CTGCCCCCTGAGGACCGGCGGCACTGGGAGATAGGAGAGGGTGGCGACAGTGGCCTGACC ATCGAGAAGTCCTGGAGGGAGCTGGTGCCTGGGCACAAGGAGATGAGCCAGGAGCTCTGC CACCAACAGGAGGCCCTGTGGGAGCTCCTGACCACCGAGCTGATCTACGTGAGAAAGCTC AAGATCATGACTGATCTGCTAGCCGCCGGCCTGCTGAACCTGCAGCGAGTGGGACTGCTG ATGGAAGTGTCAGCTGAGACCCTGTTTGGAAATGTCCCCAGCCTGATTCGAACCCACCGG AGCTTTTGGGATGAGGTGCTGGGGCCCACCCTGGAGGAGACTCGGGCCTCGGGCCAGCCT CTGGACCCCATTGGTCTGCAAAGTGGCTTCCTGACGTTTGGCCAGCGGTTCCACCCCTAT GTCCAGTACTGCCTCCGAGTGAAGCAGACCATGGCTTACGCCCGAGAACAGCAAGAAACT AACCCTCTCTTCCATGCCTTCGTGCAGTGGTGTGAGAAGCACAAGCGCTCTGGGAGGCAG ATGCTCTGTGACTTGCTTATCAAGCCCCACCAGCGCATCACCAAGTACCCACTGCTGCTC CATGCTGTGCTCAAGAGGAGCCCCGAGGCACGAGCCCAAGAGGCCCTGAATGCCATGATT GAAGCCGTGGAGTCATTCCTGCGACACATCAATGGGCAGGTCCGCCAGGGCGAAGAGCAA GAGAGCTTGGCGGCTGCAGCACAACGCATCGGGCCCTACGAGGTGCTGGAGCCACCCAGT GATGAGGTGGAGAAGAACCTGCGCCCATTCTCCACCCTGGACCTGACGTCCCCCATGCTG GGGGTTGCATCTGAGCACACCAGACAGCTGCTGCTGGAGGGGCCTGTGCGAGTGAAGGAG GGACGAGAAGGGAAGCTGGACGTGTACCTGTTCCTCTTCTCTGATGTGCTCCTTGTGACC AAGCCCCAGCGCAAGGCGGACAAAGCCAAGGTCATCCGACCCCCTCTCATGCTGGAGAAG CTCGTGTGCCAACCCCTGCGAGACCCCAACAGCTTCCTGCTGATCCACCTCACTGAATTC CAGTGTGTCTCCAGCGCCCTCCTTGTGCACTGTCCCAGTCCTACAGACCGTGCCCAGTGG CTGGAGAAGACCCAGCAGGCCCAGGCCGCCCTACAGAAGCTGAAGGCAGAGGAGTATGTT CAACAGAAGAGGGAGCTCCTGACCCTCTATCGGGACCAGGACAGGGAGTCCCCCAGCACC AGGCCCTCCACGCCTTCCCTGGAGGGCTCTCAGAGCAGCGCAGAGGGGAGGACTCCTGAG TTCTCGACCATTATCCCCCACCTGGTGGTGACAGAAGACACAGATGAAGATGCTCCCCTT GTGCCAGATGATACCTCAGACTCTGGCTACGGCACTTTGATCCCAGGCACCCCCACGGGG TCCCGCTCCCCACTGAGCCGTCTACGCCAAAGAGCCCTTCGGCGGGACCCTCGCCTCACC TTCTCCACCCTGGAACTCCGGGACATCCCTCTGCGTCCCCACCCTCCCGACCCCCAAGCT CCTCAACGCCGAAGCGCCCCCGAACTGCCGGAAGGAATCCTAAAAGGAGGCAGTCTTCCC CAGGAAGACCCACCAACCTGGTCTGAGGAAGAAGATGGGGCCTCCGAGCGAGGGAATGTG GTGGTGGAAACACTCCACAGGGCCCGGCTTCGGGGCCAGCTTCCCTCCTCCCCAACCCAT GCTGACTCTGCCGGGGAAAGCCCCTGGGAGTCCTCAGGGGAGGAGGAAGAAGAGGGGCCT CTGTTCCTGAAAGCTGGCCACACATCCCTGCGCCCAATGCGGGCTGAGGACATGCTCAGA GAGATCCGGGAGGAGCTGGCCAGCCAAAGGATTGAGGGGGCCGAGGAGCCCCGGGACAGC AGGCCACGGAAGCTGACTCGGGCCCAGCTGCAGAGGATGCGGGGGCCCCACATCATTCAG CTGGACACCCCTCTGTCCGCATCAGAGGTA |
| Restriction Sites | Please inquire |
| ACCN | NM_001144856 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001144856.1, NP_001138328.1 |
| RefSeq Size | 2981 bp |
| RefSeq ORF | 2373 bp |
| Locus ID | 55200 |
| UniProt ID | Q3KR16 |
| Gene Summary | Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHOG. Does not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same isoform (a). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC227354 | PLEKHG6 (Myc-DDK-tagged)-Human pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (PLEKHG6), transcript variant 2 |
CNY 5784.00 |
|
| RC227354L3 | Lenti-ORF clone of PLEKHG6 (Myc-DDK-tagged)-Human pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (PLEKHG6), transcript variant 2 |
CNY 5890.00 |
|
| RC227354L4 | Lenti-ORF clone of PLEKHG6 (mGFP-tagged)-Human pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (PLEKHG6), transcript variant 2 |
CNY 5890.00 |
|
| RG227354 | PLEKHG6 (tGFP-tagged) - Human pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (PLEKHG6), transcript variant 2 |
CNY 4370.00 |
