MAPKBP1 (NM_001128608) Human Untagged Clone
CAT＃: SC323281
MAPKBP1 (untagged)-Human mitogen-activated protein kinase binding protein 1 (MAPKBP1), transcript variant 2
CNY 10450.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | JNKBP-1; JNKBP1; NPHP20 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001128608, the custom clone sequence may differ by one or more nucleotides
ATGGCTGTGGAAGGGTCAACCATTACCAGCCGGATCAAGAATCTGTTGAGATCTCCATCC ATCAAACTGCGCAGGAGTAAGGCAGGAAACCGACGAGAGGACCTCAGCTCCAAGGTGACC TTGGAGAAGGTGCTGGGAATTACAGTGTCTGGAGGCAGAGGACTTGCCTGTGACCCCCGA TCAGGTTTAGTTGCTTACCCAGCAGGGTGTGTGGTTGTGTTGTTCAATCCCCGGAAACAC AAACAGCACCACATCCTCAACAGTTCCAGGAAAACCATCACTGCCCTTGCCTTCTCCCCT GATGGCAAGTACTTGGTCACTGGAGAGAGTGGGCACATGCCTGCCGTGCGGGTTTGGGAC GTGGCAGAGCACAGCCAGGTGGCCGAGCTGCAGGAGCACAAGTATGGTGTGGCTTGTGTG GCCTTCTCTCCTAGCGCCAAGTACATTGTCTCTGTGGGCTACCAGCATGACATGATCGTC AACGTGTGGGCCTGGAAGAAAAACATTGTGGTGGCCTCCAACAAGGTGTCCAGTCGGGTG ACAGCAGTGTCCTTCTCTGAGGATTGCAGCTACTTTGTCACTGCAGGCAACCGACACATC AAATTCTGGTATCTCGATGACAGCAAGACCTCAAAGGTGAATGCCACTGTGCCCTTGCTG GGCCGCTCAGGGCTGCTGGGAGAGCTACGGAACAACCTATTCACTGATGTGGCCTGTGGC AGAGGAAAAAAGGCGGACAGTACCTTCTGCATCACGTCCTCAGGGCTGCTGTGCGAGTTC AGTGATCGAAGGCTTTTGGACAAGTGGGTGGAGCTGAGGAACATAGACAGCTTCACAACC ACAGTGGCCCACTGCATCTCTGTGAGCCAAGACTACATCTTCTGTGGCTGTGCTGATGGC ACCGTGCGCCTTTTCAACCCCTCTAACCTGCACTTCCTTAGCACCTTGCCCCGACCCCAT GCTCTGGGGACAGACATTGCTAGCGTCACCGAGGCCAGTCGCCTCTTCTCTGGAGTGGCG AATGCCAGGTATCCAGACACCATTGCCTTGACCTTTGATCCTACTAATCAGTGGCTGTCT TGTGTGTACAACGATCATAGCATTTATGTTTGGGATGTGAGGGACCCCAAGAAAGTGGGC AAGGTGTACTCGGCTCTGTATCATTCTTCCTGCGTCTGGAGTGTGGAGGTCTACCCCGAG GTGAAGGATAGTAACCAGGCCTGCCTGCCCCCCAGTTCCTTTATTACCTGCTCCTCAGAC AACACCATCCGCCTGTGGAACACAGAGAGCTCCGGGGTGCATGGCTCCACCCTCCACCGA AACATCCTCAGCAGTGACCTCATTAAAATCATCTATGTGGATGGGAACACCCAGGCCCTG CTGGACACAGAGCTGCCTGGAGGAGACAAAGCTGATGCATCCCTGTTGGATCCCCGCGTG GGCATCCGCTCGGTGTGTGTCAGCCCCAATGGACAGCATCTAGCATCAGGGGACCGTATG GGCACACTTAGGGTGCACGAACTTCAGTCCCTGAGTGAGATGCTGAAGGTGGAGGCCCAT GACTCTGAGATTCTGTGCCTGGAGTATTCTAAGCCAGACACAGGTCTGAAACTGCTAGCA TCGGCGAGCCGGGACCGGCTGATCCATGTGCTGGATGCCGGGCGGGAGTACAGCCTACAG CAGACGCTGGACGAACACTCATCCTCCATCACTGCTGTTAAGTTTGCAGCCAGTGATGGG CAAGTCCGCATGATCAGCTGTGGAGCAGACAAGAGCATCTACTTCCGCACTGCGCAGAAG TCTGGAGATGGAGTGCAGTTCACACGGACACACCACGTGGTGCGGAAGACGACCCTCTAT GACATGGATGTGGAGCCCAGCTGGAAGTACACGGCTATCGGCTGCCAGGACCGAAATATT CGGATATTTAACATCAGCAGTGGAAAGCAGAAGAAGCTGTTTAAAGGGTCACAGGGTGAG GACGGCACACTCATTAAGGTGCAGACAGACCCCTCAGGGATCTACATTGCCACCAGCTGT TCTGACAAGAATCTCTCCATTTTTGACTTCTCCTCAGGCGAGTGCGTGGCCACCATGTTT GGCCACTCAGAGATTGTCACTGGCATGAAATTTAGTAATGATTGTAAACATCTCATCTCT GTGTCTGGGGACAGCTGCATATTTGTGTGGCGCCTGAGCTCTGAGATGACCATCAGCATG AGGCAGCGTCTGGCCGAGTTGCGCCAGCGTCAGCGGGGCGGCAAGCAGCAAGGACCATCC TCTCCCCAAAGGGCTTCTGGACCCAACCGGCACCAGGCCCCATCAATGCTGTCTCCTGGA CCGGCTCTCTCATCAGACAGTGACAAGGAGGGAGAAGATGAGGGGACTGAAGAAGAACTT CCAGCACTGCCCGTCCTTGCCAAGAGTACCAAGAAGGCACTGGCCTCGGTCCCCAGCCCA GCTTTGCCCCGAAGCCTGTCCCACTGGGAGATGAGTCGGGCACAGGAGTCCGTGGGGTTC CTGGACCCAGCTCCTGCAGCCAACCCAGGACCCAGAAGAAGAGGGCGCTGGGTTCAGCCA GGTGTGGAACTGAGCGTTAGATCCATGCTGGATCTGCGGCAGCTGGAAACACTGGCCCCA AGCCTGCAGGACCCTAGCCAGGACTCGCTGGCCATCATCCCATCTGGTCCCAGGAAGCAT GGGCAGGAGGCCCTTGAGACTTCACTCACTAGCCAGAATGAAAAGCCCCCTCGGCCTCAG GCTTCCCAACCTTGTTCCTATCCCCATATTATCCGATTATTGTCACAAGAGGAAGGGGTC TTTGCCCAAGATCTGGAACCTGCACCCATTGAAGATGGTATTGTCTACCCGGAGCCGAGT GACAACCCCACCATGGATACCAGTGAGTTCCAAGTGCAGGCTCCAGCCCGGGGAACTCTG GGAAGAGTGTACCCAGGCAGCAGGAGCTCAGAAAAGCACAGCCCTGACAGTGCCTGCTCT GTGGATTACAGCAGCAGCTGCCTTTCCAGCCCGGAGCACCCCACTGAAGACTCTGAGAGC ACGGAGCCCCTCAGTGTGGATGGCATCTCCTCAGACCTTGAAGAGCCAGCTGAGGGTGAT GAAGAAGAGGAAGAAGAGGAGGGAGGCATGGGCCCCTATGGGCTACAGGAGGGCAGCCCC CAGACTCCAGACCAGGAGCAGTTTCTAAAACAGCACTTTGAGACTCTGGCCAGTGGAGCT GCTCCAGGGGCCCCAGTGCAGGTCCCAGAGAGGTCAGAGTCTCGGAGTATCTCTTCACGA TTCCTGTTGCAAGTACAGACCCGCCCACTCAGGGAACCATCCCCATCCTCCTCAAGCCTG GCACTGATGTCGAGACCAGCCCAGGTGCCACAGGCATCTGGTGAGCAGCCGAGAGGCAAT GGTGCCAATCCCCCTGGAGCACCCCCGGAGGTGGAACCGTCCTCTGGCAACCCCAGCCCC CAGCAGGCAGCCTCTGTGCTGTTGCCACGATGCCGTCTCAACCCTGACAGCAGCTGGGCT CCCAAGAGAGTGGCCACAGCCAGCCCCTTTTCTGGACTCCAGAAGGCCCAGTCTGTGCAC AGTCTGGTGCCACAGGAAAGACATGAGGCCAGTCTGCAGGCCCCTTCACCAGGCGCACTG CTGTCTCGGGAGATCGAAGCTCAGGATGGTCTGGGCTCCCTGCCCCCAGCTGATGGCCGT CCGTCTCGGCCTCACTCCTATCAGAACCCCACCACCAGTTCCATGGCCAAGATATCCCGC AGTATCTCTGTTGGGGAGAACCTGGGCCTGGTGGCTGAACCTCAAGCTCATGCCCCCATC CGAGTCTCACCACTCAGCAAGCTGGCCCTGCCCAGCCGGGCTCACCTGGTCCTGGACATC CCCAAACCACTGCCTGACCGTCCTACCCTGGCTGCATTCTCTCCTGTCACCAAAGGCCGG GCCCCTGGCGAGGCAGAAAAGCCTGGCTTCCCGGTGGGCCTAGGAAAAGCTCACAGTACA ACTGAGAGATGGGCCTGTTTGGGGGAGGGCACCACTCCCAAGCCTAGGACAGAGTGCCAG GCTCATCCTGGGCCCAGCAGCCCCTGTGCCCAGCAACTGCCAGTCAGCAGCCTCTTCCAA GGCCCTGAAAACTTGCAGCCCCCACCCCCTGAGAAGACTCCCAACCCCATGGAATGCACC AAGCCAGGGGCAGCCCTGAGCCAGGACTCAGAGCCAGCGGTGAGCCTGGAGCAGTGTGAG CAGCTGGTGGCAGAGCTCCGCGGCAGCGTGCGCCAGGCAGTGCGGCTCTACCACTCGGTG GCTGGCTGCAAGATGCCCTCAGCAGAGCAAAGTCGGATTGCCCAGCTCCTCAGAGACACC TTCTCTTCAGTGCGACAGGAGCTGGAAGCTGTGGCTGGGGCAGTGCTGTCCAGCCCAGGC AGCAGCCCTGGGGCTGTGGGAGCCGAGCAGACACAGGCCCTGCTGGAGCAATACTCAGAA CTGTTGCTTCGAGCCGTGGAACGGCGTATGGAACGCAAACTC |
| Restriction Sites | Please inquire |
| ACCN | NM_001128608 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001128608.1, NP_001122080.1 |
| RefSeq Size | 7265 bp |
| RefSeq ORF | 4545 bp |
| Locus ID | 23005 |
| UniProt ID | O60336 |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients. [provided by RefSeq, May 2017] Transcript Variant: This variant (2) includes an alternate exon in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (b) is longer than isoform a. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC226405 | MAPKBP1 (Myc-DDK-tagged)-Human mitogen-activated protein kinase binding protein 1 (MAPKBP1), transcript variant 2 |
CNY 10360.00 |
|
| RC226405L3 | Lenti-ORF clone of MAPKBP1 (Myc-DDK-tagged)-Human mitogen-activated protein kinase binding protein 1 (MAPKBP1), transcript variant 2 |
CNY 17010.00 |
|
| RC226405L4 | Lenti-ORF clone of MAPKBP1 (mGFP-tagged)-Human mitogen-activated protein kinase binding protein 1 (MAPKBP1), transcript variant 2 |
CNY 17010.00 |
|
| RG226405 | MAPKBP1 (tGFP-tagged) - Human mitogen-activated protein kinase binding protein 1 (MAPKBP1), transcript variant 2 |
CNY 16630.00 |
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