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FVT1 (KDSR) (NM_002035) Human Untagged Clone
CAT＃: SC321528
KDSR (untagged)-Human 3-ketodihydrosphingosine reductase (KDSR)
CNY 3,600.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DHSR; EKVP4; FVT1; SDR35C1 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_002035.1
GCCCCGGCCCGCAAACCCAAACACTCCAGGCGCCCGCCCGCCGCGCGTGATTCTCGCCTC
GCCGCAGCCCAGCCCTGCGCGCCTTGCCCGGCGGCCCCCGCCCGGCCGCTCCGGGCCCCT GGCCCCGCGGAGCGATGCTGCTGCTGGCTGCCGCCTTCCTCGTGGCCTTCGTGCTGCTGC TGTACATGGTGTCTCCGCTCATCAGCCCCAAGCCCCTCGCCCTGCCCGGGGCGCATGTGG TGGTTACAGGAGGTTCCAGTGGCATCGGGAAGTGCATTGCTATCGAGTGCTATAAACAAG GAGCTTTTATAACTCTGGTTGCACGAAATGAGGATAAGCTGCTGCAGGCAAAGAAAGAAA TTGAAATGCACTCTATTAATGACAAACAGGTGGTACTTTGCATATCAGTTGATGTATCTC AAGACTATAACCAAGTAGAGAATGTCATAAAACAAGCACAGGAGAAACTGGGTCCAGTGG ACATGCTGGTAAATTGTGCAGGAATGGCAGTGTCAGGAAAATTTGAAGATCTTGAAGTTA GTACCTTTGAAAGGTTAATGAGCATCAATTACCTGGGCAGCGTGTACCCCAGCCGGGCCG TGATCACCACCATGAAGGAGCGCCGGGTGGGCAGGATCGTGTTTGTGTCCTCCCAGGCAG GACAGTTGGGATTATTCGGTTTCACAGCCTACTCTGCATCCAAGTTTGCCATAAGGGGAT TGGCAGAAGCTTTGCAGATGGAGGTGAAGCCATATAATGTCTACATCACAGTTGCTTACC CACCAGACACAGACACACCTGGCTTTGCCGAAGAAAACAGAACAAAGCCTTTGGAGACTC GACTTATTTCAGAGACCACATCTGTGTGCAAACCAGAACAGGTGGCCAAACAAATTGTTA AAGATGCCATACAAGGAAATTTCAACAGTTCCCTTGGCTCAGATGGGTACATGCTCTCGG CCCTGACCTGTGGGATGGCTCCAGTAACTTCTATTACTGAGGGGCTCCAGCAGGTGGTCA CCATGGGCCTTTTCCGCACTATTGCTTTGTTTTACCTTGGAAGTTTTGACAGCATAGTTC GTCGCTGCATGATGCAGAGAGAAAAATCTGAAAATGCAGACAAAACTGCCTAATCTTCTT ACCCCTTGGAAGAAGACTGTTTCCAAATAATTTGAACAGCTTGCTGCTAAATGGGACCCA ATTTTTGGCCTATAGACACTTATGTATTGTTTTCGAATACGTCAGATTGGACCAGTGCTC TTCAGGAATGTGGCTGCAAGCAAGGGGCTAGAAGTTCACCTCCTGACAGTATTATTAATA CTATGCAAATATGGAATAGGAGACCATTTGATTTTCTAGGCTTTGTGGTAGAGAGGTGAA GGTATGAGAATTAATAGCGTGTGAACAAAGTAAAGAACAGGATTCCAGAATGATCATTAA ATTTGTTTCTATTTATTCTTTTTTGCCCCCCTAGAGATTAAGTCCAGAAATGTACTTTCT GGCACATAAAGAAATCTTGAGGACTTTGTTTAAACCTTCCATAAAAAAACAATTTTGCTT ATACTGCTGTAATATTTTTGTAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_002035 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002035.1, NP_002026.1 |
| RefSeq Size | 2272 bp |
| RefSeq ORF | 999 bp |
| Locus ID | 2531 |
| UniProt ID | Q06136 |
| Domains | adh_short |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Metabolic pathways, Sphingolipid metabolism |
| Gene Summary | The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201153 | KDSR (Myc-DDK-tagged)-Human 3-ketodihydrosphingosine reductase (KDSR) |
CNY 3,600.00 |
|
| RC201153L3 | Lenti ORF clone of Human 3-ketodihydrosphingosine reductase (KDSR), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201153L4 | Lenti ORF clone of Human 3-ketodihydrosphingosine reductase (KDSR), mGFP tagged |
CNY 5,890.00 |
|
| RG201153 | KDSR (tGFP-tagged) - Human 3-ketodihydrosphingosine reductase (KDSR) |
CNY 5,200.00 |
