MLSTD2 (FAR1) (NM_032228) Human Untagged Clone
CAT#: SC321231
FAR1 (untagged)-Human fatty acyl CoA reductase 1 (FAR1)
CNY 3840.00
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CSPSD; MLSTD2; PFCRD; SDR10E1 |
Vector | pCMV6-AC |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>OriGene sequence for NM_032228.4
GAGTGAAGAGAGCGCGACGGCGGCGGCGGCGGCGGCGCAGCTATTGCTGGACGGCCAGTG
GGAGAGCGAGGCCTGAGCCTCTGCGTCTAGGATCAAAATGGTTTCAATCCCAGAATACTA TGAAGGCAAGAACGTCCTCCTCACAGGAGCTACCGGTTTTCTAGGGAAGGTGCTTCTGGA AAAGTTGCTGAGGTCTTGTCCTAAGGTGAATTCAGTATATGTTTTGGTGAGGCAGAAAGC TGGACAGACACCACAAGAGCGAGTGGAAGAAGTCCTTAGTGGCAAGCTTTTTGACAGATT GAGAGATGAAAATCCAGATTTTAGAGAGAAAATTATAGCAATCAACAGCGAACTCACCCA ACCTAAACTGGCTCTCAGTGAAGAAGATAAAGAGGTGATCATAGATTCTACCAATATTAT ATTCCACTGTGCAGCTACAGTAAGGTTTAATGAAAATTTAAGAGATGCTGTTCAGTTAAA TGTGATTGCAACGCGACAGCTTATTCTCCTTGCACAACAAATGAAGAATCTGGAAGTGTT CATGCATGTATCAACAGCATATGCCTACTGTAATCGCAAGCATATTGATGAAGTAGTCTA TCCACCACCTGTGGATCCCAAGAAGCTGATTGATTCTTTAGAGTGGATGGATGATGGCCT AGTAAATGATATCACGCCAAAATTGATAGGAGACAGACCTAATACATACATATACACAAA AGCATTGGCAGAATATGTTGTACAACAAGAAGGAGCAAAACTAAATGTGGCAATTGTAAG GCCATCGATTGTTGGTGCCAGTTGGAAAGAACCTTTTCCAGGATGGATTGATAACTTTAA TGGACCAAGTGGTCTCTTTATTGCGGCAGGGAAAGGAATTCTTCGAACAATACGTGCCTC CAACAATGCCCTTGCAGATCTTGTTCCTGTAGATGTAGTTGTCAACATGAGTCTTGCGGC AGCCTGGTATTCCGGAGTTAATAGACCAAGAAACATCATGGTGTATAATTGTACAACAGG CAGCACTAATCCTTTCCACTGGGGTGAAGTTGAGTACCATGTAATTTCCACTTTCAAGAG GAATCCTCTCGAACAGGCCTTCAGACGGCCCAATGTAAATCTAACCTCCAATCATCTTTT ATATCATTACTGGATTGCTGTAAGCCATAAGGCCCCAGCATTCCTGTATGATATCTACCT CAGGATGACTGGAAGAAGCCCAAGGATGATGAAAACAATAACTCGTCTTCACAAAGCTAT GGTGTTTCTTGAATATTTCACAAGTAATTCTTGGGTTTGGAATACTGAGAATGTCAATAT GTTAATGAATCAACTAAACCCTGAAGATAAAAAGACCTTCAATATTGATGTACGGCAGTT ACATTGGGCAGAATATATAGAGAACTACTGCTTGGGAACTAAGAAGTACGTATTGAATGA AGAAATGTCTGGCCTCCCTGCAGCCAGAAAACATCTGAACAAGTTGCGGAATATACGTTA TGGTTTTAATACTATCCTTGTGATCCTCATCTGGCGCATTTTTATTGCAAGATCACAAAT GGCAAGAAATATCTGGTACTTTGTGGTTAGTCTGTGTTACAAGTTTTTGTCATACTTCCG AGCATCCAGCACTATGAGATACTGAAGACCAAGGATTCAGCATTAGAACATCTATACATA TGGTGATCTAAATGTACAAAATGTAAAATGTATAAGTCATCTCACTTTTTGTCAAGACAT TAAACCATCTTAGATCGAAAAAAAAAAAAAAAAAAAAAAAA |
Restriction Sites | Please inquire |
ACCN | NM_032228 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_032228.4, NP_115604.1 |
RefSeq Size | 5224 bp |
RefSeq ORF | 1548 bp |
Locus ID | 84188 |
UniProt ID | Q8WVX9 |
Domains | Sterile |
Protein Families | Transmembrane |
Gene Summary | The protein encoded by this gene is required for the reduction of fatty acids to fatty alcohols, a process that is required for the synthesis of monoesters and ether lipids. NADPH is required as a cofactor in this reaction, and 16-18 carbon saturated and unsaturated fatty acids are the preferred substrate. This is a peroxisomal membrane protein, and studies suggest that the N-terminus contains a large catalytic domain located on the outside of the peroxisome, while the C-terminus is exposed to the matrix of the peroxisome. Studies indicate that the regulation of this protein is dependent on plasmalogen levels. Mutations in this gene have been associated with individuals affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity (PMID: 25439727). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jan 2015] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC203615 | FAR1 (Myc-DDK-tagged)-Human fatty acyl CoA reductase 1 (FAR1) |
CNY 3832.00 |
|
RC203615L3 | Lenti ORF clone of Human fatty acyl CoA reductase 1 (FAR1), Myc-DDK-tagged |
CNY 6460.00 |
|
RC203615L4 | Lenti ORF clone of Human fatty acyl CoA reductase 1 (FAR1), mGFP tagged |
CNY 6460.00 |
|
RG203615 | FAR1 (tGFP-tagged) - Human fatty acyl CoA reductase 1 (FAR1) |
CNY 5040.00 |