DUSP8 (NM_004420) Human Untagged Clone
CAT＃: SC320558
DUSP8 (untagged)-Human dual specificity phosphatase 8 (DUSP8)
CNY 6992.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C11orf81; HB5; HVH-5; HVH8 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_004420.1
CATGGCTGGGGACCGGCTCCCGAGGAAGGTGATGGATGCCAAGAAGCTGGCCAGCCTGCT
GCGGGGCGGGCCTGGGGGGCCGCTGGTCATCGACAGCCGCTCCTTCGTGGAGTACAACAG CTGGCATGTGCTCAGCTCCGTCAACATCTGCTGCTCCAAGCTGGTGAAGCGGCGGCTGCA GCAGGGCAAGGTGACCATTGCGGAGCTCATCCAGCCGGCTGCACGCAGCCAGGTGGAGGC TACGGAGCCACAGGACGTGGTGGTCTATGACCAGAGCACGCGGGACGCCAGCGTGCTGGC CGCAGACAGCTTCCTCTCCATCCTGCTGAGCAAGCTGGACGGCTGCTTCGACAGCGTGGC CATCCTCACTGGGGGCTTCGCCACCTTCTCCTCCTGCTTCCCCGGCCTCTGCGAGGGCAA GCCTGCTGCCCTGCTACCCATGAGCCTCTCCCAGCCCTGCCTGCCTGTGCCCAGCGTGGG CCTCACCCGCATCCTGCCTCACCTCTACCTGGGCTCGCAGAAGGACGTCCTAAACAAGGA TCTGATGACGCAAAATGGAATAAGCTACGTCCTCAACGCCAGCAACTCCTGCCCCAAGCC TGACTTCATCTGCGAGAGCCGCTTCATGCGGGTCCCCATCAACGACAACTACTGTGAAAA ACTGCTGCCCTGGCTGGACAAGTCCATCGAGTTCATCGATAAAGCCAAGCTCTCCAGCTG CCAAGTCATCGTCCACTGTCTGGCTGGCATCTCCCGCTCTGCCACCATCGCCATCGCCTA CATCATGAAGACCATGGGCATGTCCTCCGACGACGCCTACAGGTTCGTGAAGGACAGGCG CCCGTCCATCTCGCCCAACTTCAACTTCCTGGGCCAGCTGCTGGAGTACGAGCGCAGCCT GAAGCTGCTGGCCGCCCTGCAGGGCGACCCGGGCACCCCCTCAGGGACGCCGGAGCCTCC GCCCAGTCCTGCCGCCGGGGCCCCGCTGCCACGGCTGCCACCACCTACCTCAGAGAGCGC TGCCACAGGGAATGCGGCTGCCAGGGAGGGCGGCCTGAGCGCGGGCGGGGAGCCCCCCGC GCCCCCCACGCCCCCGGCGACCAGCGCACTGCAGCAGGGCCTGCGCGGCCTGCACCTCTC CTCGGACCGCCTGCAGGACACTAACCGCCTCAAGCGCTCCTTCTCCCTGGACATCAAGTC TGCCTACGCCCCTAGCAGGCGGCCCGACGGCCCCGGGCCCCCCGACCCCGGCGAGGCCCC GAAGCTCTGCAAGCTGGACAGCCCGTCGGGGGCCGCGCTGGGCCTGTCCTCGCCCAGCCC GGACAGCCCGGACGCCGCGCCTGAGGCGCGCCCACGGCCCCGCCGGCGGCCCCGGCCCCC CGCCGGCTCCCCCGCGCGCTCCCCCGCGCACAGCCTCGGCCTGAACTTCGGCGATGCGGC CCGGCAGACTCCGCGGCACGGCCTCTCGGCCCTGTCGGCGCCCGGGCTGCCCGGCCCTGG CCAGCCGGCCGGCCCCGGGGCCTGGGCACCGCCGCTCGACTCCCCAGGCACGCCGTCGCC CGACGGGCCCTGGTGCTTCAGCCCCGAGGGCGCACAGGGGGCGGGCGGGGTGCTGTTTGC GCCCTTCGGCCGGGCGGGCGCCCCGGGACCAGGCGGCGGCAGCGACCTGCGGCGGCGGGA GGCAGCGAGGGCTGAGCCCCGGGACGCGCGGACCGGCTGGCCCGAGGAGCCGGCCCCGGA GACGCAGTTCAAGCGCCGCAGCTGCCAGATGGAGTTCGAGGAGGGCATGGTGGAGGGGCG CGCGCGCGGCGAGGAGCTGGCCGCCCTGGGCAAGCAGGCGAGCTTCTCGGGCAGCGTGGA GGTCATCGAGGTGTCCTGACCCCTCCGCTGCCCTCGGCCCCGCCGCCCGCAGCCAGGCCC GTTATAAATGTATATTATATATAATGCAAAGAAAGGTAAATGGTTTTACTGGGATTTTTA TCGAGAAGTAAATATTTCGATTTTTTATTTATTTAAGCTGTTCATTCTGGCAATGATTTG GCAACAGTGCGGGTGGTCCTCGAGCTCTATTTTTACTGTCTGGTATTTAAACTGAAACAT ACGTTTCTAAGCAATACGAGGCCACCTTCAGTCGCAAGCTGGGTGCCAGGCCTGGGGCCC CTCCCAGTTCCCCCGCCCCAGGAAACACTGCTGACCTTTGCAAAGGCTGCCGAGCTTTCG TGCACTTTTTACATAACAAAAAGGTGAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_004420 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004420.1, NP_004411.1 |
| RefSeq Size | 2377 bp |
| RefSeq ORF | 1878 bp |
| Locus ID | 1850 |
| UniProt ID | Q13202 |
| Protein Families | Druggable Genome, Phosphatase |
| Protein Pathways | MAPK signaling pathway |
| Gene Summary | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208337 | DUSP8 (Myc-DDK-tagged)-Human dual specificity phosphatase 8 (DUSP8) |
CNY 6976.00 |
|
| RC208337L1 | Lenti ORF clone of Human dual specificity phosphatase 8 (DUSP8), Myc-DDK-tagged |
CNY 9376.00 |
|
| RC208337L2 | Lenti ORF clone of Human dual specificity phosphatase 8 (DUSP8), mGFP tagged |
CNY 5890.00 |
|
| RC208337L3 | Lenti ORF clone of Human dual specificity phosphatase 8 (DUSP8), Myc-DDK-tagged |
CNY 5890.00 |
|
| RC208337L4 | Lenti ORF clone of Human dual specificity phosphatase 8 (DUSP8), mGFP tagged |
CNY 9376.00 |
|
| RG208337 | DUSP8 (tGFP-tagged) - Human dual specificity phosphatase 8 (DUSP8) |
CNY 4370.00 |
|
| SC303480 | DUSP8 (untagged)-Human dual specificity phosphatase 8 (DUSP8) |
CNY 10070.00 |
