ATXN7L3 (NM_001098833) Human Untagged Clone
CAT＃: SC316504
ATXN7L3 (untagged)-Human ataxin 7-like 3 (ATXN7L3), transcript variant 2
CNY 7220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DKFZp761G2113 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC316504 representing NM_001098833.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGAAAATGGAGGAAATGTCTTTGTCTGGCCTGGATAACAGCAAACTAGAGGCCATCGCTCAGGAGATA TACGCGGACCTGGTCGAGGATTCTTGTTTGGGATTCTGCTTTGAGGTACACCGGGCTGTCAAGTGTGGC TACTTCTTCTTGGACGACACGGACCCTGATAGCATGAAGGATTTTGAGATCGTGGACCAGCCGGGCTTG GACATCTTTGGACAGGTTTTCAACCAGTGGAAGAGCAAGGAGTGTGTTTGCCCCAATTGCAGTCGCAGC ATTGCCGCCTCCCGCTTTGCTCCCCATCTGGAGAAGTGCCTGGGAATGGGTCGGAACAGCAGCCGAATC GCCAACCGCCGGATTGCCAATAGCAACAATATGAATAAGTCTGAGAGTGACCAAGAAGATAATGATGAC ATCAATGACAACGACTGGTCCTATGGCTCGGAGAAGAAAGCCAAGAAGAGAAAGTCAGACAAGAACCCC AATTCCCCTCGAAGATCCAAGTCATTAAAACACAAAAATGGGGAACTTAGCAATTCGGATCCTTTTAAG TATAACAATTCAACTGGGATCAGCTATGAGACCCTGGGGCCGGAGGAGCTTCGCAGCCTGCTAACCACG CAATGTGGGGTGATTTCTGAACACACCAAGAAGATGTGCACAAGGTCCCTGCGCTGCCCACAGCACACA GATGAGCAGAGGCGAACCGTACGGATTTATTTTCTCGGGCCCTCGGCTGTCCTTCCAGAGGTCGAGAGC TCCCTGGATAATGACAGCTTTGACATGACTGACAGCCAGGCCCTGATCAGCCGGCTTCAGTGGGACGGC TCCTCTGACCTCTCACCCTCTGATTCAGGCTCCTCCAAGACGAGTGAAAATCAGGGATGGGGTCTAGGT ACCAACAGCTCTGAGTCACGGAAAACCAAGAAAAAGAAATCCCATCTGAGCCTGGTAGGGACTGCCTCC GGCCTAGGTTCCAACAAGAAGAAGAAGCCAAAGCCACCGGCACCCCCGACGCCCAGCATCTATGATGAC ATCAACTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001098833 |
| Insert Size | 1044 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001098833.1 |
| RefSeq Size | 3635 bp |
| RefSeq ORF | 1044 bp |
| Locus ID | 56970 |
| UniProt ID | Q14CW9 |
| MW | 38.7 kDa |
| Gene Summary | Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B (PubMed:18206972, PubMed:21746879). The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex (PubMed:18206972). Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B (PubMed:27601583).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216661 | ATXN7L3 (Myc-DDK-tagged)-Human ataxin 7-like 3 (ATXN7L3), transcript variant 2 |
CNY 3656.00 |
|
| RC216661L3 | Lenti ORF clone of Human ataxin 7-like 3 (ATXN7L3), transcript variant 2, Myc-DDK-tagged |
CNY 5890.00 |
|
| RC216661L4 | Lenti ORF clone of Human ataxin 7-like 3 (ATXN7L3), transcript variant 2, mGFP tagged |
CNY 5890.00 |
|
| RG216661 | ATXN7L3 (tGFP-tagged) - Human ataxin 7-like 3 (ATXN7L3), transcript variant 2 |
CNY 4370.00 |
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