BEND3 (NM_001080450) Human Untagged Clone
CAT＃: SC315838
BEND3 (untagged)-Human BEN domain containing 3 (BEND3)
CNY 7220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | KIAA1553 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC315838 representing NM_001080450.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGAACTCAACTGAATTCACCGAAGATGTAGAAGAAGTTCTAAAAAGTATCACTGTGAAAGTGGAGACA GAGGCTGAAGATGCTGCTCTGGACTGCTCCGTGAATTCCAGGACTTCTGAGAAGCACTCTGTGGACAGC GTCCTCACTGCCCTGCAGGACTCCAGCAAACGAAAGCAGCTGGTCAGCGATGGCCTGCTAGACTCTGTC CCCGGCGTGAAGAGGAGGCGGCTGATCCCCGAGGCTCTCCTAGCAGGCATGCGGAACCGTGAGAACAGC TCGCCCTGCCAAGGCAATGGTGAGCAGGCCGGCAGGGGCAGGAGCCTGGGCAATGTGTGGCCTGGAGAG GAGGAGCCCTGCAACGATGCCACCACCCCTTCCTACAAGAAGCCTCTGTATGGCATCTCGCACAAGATC ATGGAGAAGAAGAATCCTCCCTCGGGGGACCTGCTAAACGTGTACGAGCTCTTTGAGAAGGCAAACGCC AGCAACAGCCCCTCGTCACTGCGGCTCCTGAATGAGCCACAGAAGCGGGACTGTGGCAGCACCGGGGCA GGCACTGACAACGACCCCAACATCTACTTCCTGATCCAGAAGATGTTCTACATGCTGAACACCCTCACG TCCAACATGTCCCAGCTGCACAGCAAGGTGGACCTGCTCTCCCTTGAGGTGAGCCGCATCAAGAAGCAG GTGAGCCCCACTGAGATGGTGGCCAAATTCCAGCCGCCCCCTGAGTACCAGCTCACAGCCGCAGAGCTC AAGCAGATCGTGGACCAGAGCCTGTCAGGGGGGGACCTGGCCTGCCGCTTGCTGGTGCAGCTCTTCCCC GAGCTCTTCAGCGACGTGGACTTCTCCCGGGGCTGCAGTGCCTGTGGCTTTGCGGCCAAGCGCAAGCTG GAGTCGCTGCACCTGCAGCTCATCCGCAACTATGTGGAGGTCTACTACCCCTCGGTGAAGGACACGGCT GTGTGGCAGGCCGAGTGCCTGCCCCAGCTGAACGACTTCTTCAGCCGCTTCTGGGCCCAGCGGGAAATG GAGGACAGCCAGCCCAGCGGCCAGGTCGCCAGCTTCTTTGAGGCAGAGCAGGTGGACCCCGGCCACTTC CTGGACAACAAAGACCAGGAGGAGGCCCTGTCTCTTGACCGGAGCAGCACCATCGCCTCAGACCACGTG GTGGACACGCAGGACCTCACTGAGTTCCTGGACGAAGCCTCCTCACCAGGCGAGTTTGCCGTCTTCCTC CTCCACCGGCTCTTCCCCGAGCTCTTCGACCACCGCAAGCTGGGTGAACAGTACAGCTGCTACGGGGAC GGTGGAAAGCAGGAGCTGGACCCGCAGCGGCTGCAGATCATCCGCAACTACACGGAGATCTACTTCCCT GACATGCAGGAGGAGGAGGCCTGGCTGCAGCAGTGTGCCCAGCGCATCAACGACGAGCTCGAGGGCCTG GGGCTGGACGCGGGCAGTGAAGGCGACCCCCCGCGTGATGACTGCTACGACTCCTCCAGTCTGCCCGAC GACATCTCAGTGGTCAAGGTGGAGGACAGCTTCGAGGGCGAGCGGCCGGGTCGCCGCTCCAAGAAGATC TGGCTGGTGCCCATCGACTTCGACAAGTTAGAGATCCCCCAGCCTGACTTCGAGGTGCCCGGTGCCGAC TGCCTGCTCAGCAAGGAGCAGCTACGCAGCATCTACGAGAGCAGCCTGTCCATCGGCAACTTCGCCTCG CGCCTGCTGGTGCACCTGTTCCCCGAGCTCTTCACGCACGAGAACCTGCGCAAGCAGTACAACTGCAGC GGCTCCCTGGGCAAGAAGCAGCTGGACCCCTCCCGCATCAAGCTCATCCGCCACTACGTGCAGCTGCTC TACCCACGCGCCAAAAACGACCGCGTCTGGACCCTGGAGTTCGTGGGCAAACTGGATGAGCGCTGCCGG CGCCGGGACACGGAGCAAAGGCGCTCCTACCAGCAGCAGCGCAAGGTCCACGTGCCGGGCCCTGAGTGC AGAGACTTGACCAGCTATGCAATCAACCCCGAGAGGTTCCGGGAGGAGTTTGAGGGGCCCCCACTGCCC CCCGAGAGGAGCAGCAAGGACTTTTGCAAGATCCCCTTGGACGAGCTGGTGGTCCCCTCGCCTGACTTC CCGGTGCCTTCTCCCTACCTGCTGTCTGACAAGGAGGTGCGTGAGATCGTGCAGCAGAGCCTCTCCGTG GGCAACTTTGCCGCCCGGCTCCTCGTCCGCCTGTTTCCCGAACTCTTCACCGCCGAGAACCTCCGGCTG CAGTACAACCATTCCGGGGCTTGCAACAAGAAGCAACTGGACCCCACGCGGCTGCGGCTCATCCGCCAC TACGTGGAAGCCGTCTACCCGGTGGAGAAGATGGAGGAGGTGTGGCACTACGAATGTATCCCCAGCATC GATGAGAGGTGCCGCCGCCCCAACAGGAAAAAATGCGACATCCTCAAGAAAGCAAAGAAAGTGGAGAAG TGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001080450 |
| Insert Size | 2487 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001080450.2 |
| RefSeq Size | 6660 bp |
| RefSeq ORF | 2487 bp |
| Locus ID | 57673 |
| UniProt ID | Q5T5X7 |
| MW | 94.5 kDa |
| Gene Summary | Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination (PubMed:21914818, PubMed:26100909). Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites (By similarity). Stimulates the ERCC6L translocase and ATPase activities (PubMed:28977671).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215913 | BEND3 (Myc-DDK-tagged)-Human BEN domain containing 3 (BEND3) |
CNY 6064.00 |
|
| RC215913L3 | Lenti ORF clone of Human BEN domain containing 3 (BEND3), Myc-DDK-tagged |
CNY 7700.00 |
|
| RC215913L4 | Lenti ORF clone of Human BEN domain containing 3 (BEND3), mGFP tagged |
CNY 7700.00 |
|
| RG215913 | BEND3 (tGFP-tagged) - Human BEN domain containing 3 (BEND3) |
CNY 6370.00 |
